Table 2 King's College Hospital criteria for liver transplantation in acetaminophen-induced acute liver failure
From: Acetaminophen poisoning: an update for the intensivist
Current criteria [11] | Modified criteria [14] |
|---|---|
List for transplantation if: | Strongly consider listing for transplantation if: |
Arterial pH <7.3 after adequate fluid resuscitation | Arterial blood lactate concentration >3.5 mmol/l after early fluid resuscitation |
List for transplantation if all three of the following occur within a 24-h period: | List for transplantation if: |
• Creatinine >300 μmol/l | Arterial pH <7.3, or arterial blood lactate concentration >3.0 mmol/l after adequate fluid resuscitation |
• PT >100 s (INR >6.5) |  |
• Grade III/IV encephalopathy | List for transplantation if all three of the following occur within a 24-h period: |
|  | • Creatinine >300 μmol/l |
|  | • PT >100 s (INR >6.5) |
|  | • Grade III/IV encephalopathy |