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Table 1 Findings of 12 patients receiving AS.

From: Amantadine sulfate treatment in cases with brain injury in the ICU: a retrospective clinical trial

Initiation of Patient number AS therapy (day)

Sex/age (years) CRS score D/E/F/G

APACHE II Complications

GCS A/B/C Outcome

1

M/14

24

3/5/7

6

0/4/5/6

H, J

Still in ICU

2

F/78

33

8/8/10

84

0/0/0/0

K

Ex

3

F/75

35

5/6/4

4

1/1/0/Ex

K, L

Ex

4

M/24

29

3/3/3

6

0/0/Ex

K, L

Ex

5

M/27

27

4/4/15

6

1/13/18/22

L, M, J

Discharged

6

F/70

45

3/3/3

20

0/0/0/0

-

Ex

7

F/72

22

5/5/12

3

4/7/11/17

K, L, I

Discharged

8

F/53

27

3/5/10

150

5/7/10/14

K

Discharged

9

F/38

34

4/4/4

33

0/0/1/1

H, J

Still in ICU

10

M/50

26

4/6/13

8

0/7/18/19

L, J

Discharged

11

M/63

24

8/10/12

14

6/8/8/12

-

Discharged

12

M/50

31

4/6/11

6

2/5/7/9

L, J

Still in ICU

  1. F, female; M, male. GCS, Glasgow Coma Scale: A, at admission to ICU; B, at initiation of AS therapy; C, outcome value. CRS: D, value on day 1, E, value on day 6, F, value on day 10, G, value on day 14. Complications observed: H, low platelet; J, ALT increase by twofold; K, BUN increase by twofold; L, AST increase by twofold; M, convulsion.