C-reactive protein levels on admission are correlated with mortality and organ failures in critically ill patients
© The Author(s) 2001
Published: 26 June 2001
C-reactive protein (CRP) increases in response to infection, trauma, ischemia, burns, and inflammatory conditions. Although used frequently in the ICU setting as a marker of systemic inflammation, its relation with organ damage is not well known. This study assessed the association between early serum CRP levels and the development of organ failure (OF) and mortality in ICU patients.
A prospective cohort study conducted in a 31-bed intensive care unit of a university hospital.
A total of 307 admitted within a 4-month period.
Measurements and main outcomes
Elevated concentrations of serum CRP on admission are potential indicators of an increased risk of organ failure and dying.