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Open Access

Evaluation of thrombocytopenia in a general intensive care unit

  • NCM Youssef1,
  • CBD Roda1,
  • CEA Castilho1,
  • CA Silveira1,
  • CIM Guedes1,
  • CB Santos1,
  • FM Rodrigues1,
  • GTB Mendes1,
  • KC Abrão1 and
  • A Réa-Neto1
Critical Care20015(Suppl 3):P87

https://doi.org/10.1186/cc1420

Published: 26 June 2001

Keywords

Mortality RateIntensive Care UnitPlatelet CountThrombocytopeniaSeverity Score

Introduction

Thrombocytopenia is a common laboratory abnormality in intensive care units (ICU), and generally results from multi-factorial causes. The goal of this study was to determine the incidence of thrombocytopenia and the correlation with length of ICU stay, mortality rate, admission severity scores APACHEII and SAPSII, and multiple organ dysfunction scores SOFA and LODS.

Method

We evaluated patients admitted in a general ICU from January to July 2000 and collected the referring data to APACHEII, SAPSII, SOFA and LODS correlated with platelet count at the admission day and daily during ICU stay. We also obtained the mortality rate and the incidence of bleeding. We considered thrombocytopenia platelet count <150000.

Results

The total of 326 patients were analyzed in 7 months. The group of thrombocytopenia patients (n = 94) had longer ICU stay, higher APACHEII, SAPSII, LODS and SOFA as well as higher mortality rate.

Conclusions

Thrombocytopenia constitutes 28.90% of the population admitted at ICU and its development is predictive element for longer ICU stay and mortality rate. It is associate with worse prognosis index and higher organic dysfunction in the first day.

Table

 

Patients with

Patients with

 

thrombocytopenia

normal platelet count

n

94

232

Platelet count

111,000 ± 34,000

249,000 ± 87,000

ICU stay (days)

5.93 (± 8.66)

2.32 (± 3.20)

APACHE II

14.26 (± 7.52)

10.57 (± 6.54)

SAPS II

10.74 (± 5.46)

8.43 (± 4.43)

LODS

4.31 (± 4.12)

2.20 (± 3.05)

SOFA

3.55 (± 2.78)

1.74 (± 2.10)

Mortality rate

17 patients (18%)

11 patients (4.74%)

Authors’ Affiliations

(1)
CEPETI - Centro de Estudos e Pesquisa em Terapia Intensiva, Brazil

Copyright

© The Author(s) 2001

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