From: Early mobilization on continuous renal replacement therapy is safe and may improve filter life
Group | Factors | Regression coefficient (robust 95% CI) | P value |
---|---|---|---|
Baseline (n = 19) | INR | 0.8 (-1.4 to 3.0) | 0.44 |
aPTT | 0.1 (-0.3 to 0.5) | 0.63 | |
Platelets | 0.0 (0.0 to 0.1) | 0.09 | |
Positional changes | 1.2 (-0.4 to 2.9) | 0.13 | |
APACHE III | -0.1 (-0.3 to 0.0) | 0.09 | |
Overall cohort (MOVE intervention) (n = 33) | MOVE intervention | 13.8 (5.0 to 22.6) | 0.003b |
Overall subgroup and sensitivity analyses | Passive movements | 20.0 (5.4 to 34.6) | 0.01b |
SOEOB | 5.8 (-10.7 to 22.3) | 0.46 | |
MOS | 18.3 (-1.3 to 37.9) | 0.06 | |
INR | 9.3 (-2.0 to 20.5) | 0.10 | |
aPTT | 0.0 (-0.2 to 0.2) | 0.86 | |
Platelets | 0.0 (-0.1 to 0.0) | 0.10 | |
Positional changes | 2.0 (0.6 to 3.5) | 0.007b | |
APACHE III | 0.1 (0.0 to 0.3) | 0.02b | |
Alarms | -3.1 (-5.0 to -1.2) | 0.003b | |
Femoral subgroup (n =23) | MOVE intervention | 15.7 (4.6 to 26.9) | 0.008b |
Femoral subgroup and sensitivity analyses | Passive movements | 20.0 (5.4 to 34.6) | 0.01b |
SOEOB | 8.5 (-20.6 to 37.7) | 0.51 | |
MOS | 20.5 (-19.9 to 60.9) | 0.16 | |
INR | 7.6 (-4.9 to 20.0) | 0.22 | |
aPTT | -0.1 (-0.2 to 0.1) | 0.38 | |
Platelets | 0.0 (-0.1 to 0.0) | 0.29 | |
Positional changes | 2.0 (0.5 to 3.6) | 0.01b | |
APACHE III | 0.6 (-0.1 to 0.2) | 0.42 | |
Alarms | -7.4 (-13.0 to -1.8) | 0.01b | |
Nonfemoral subgroup (n = 10) | MOVE intervention | 9.2 (-6.0 to 24.4) | 0.20 |
Nonfemoral subgroup and sensitivity analyses | Passive movements | N/A | – |
SOEOB | 1.0 (-12.8 to 14.8) | 0.86 | |
MOS | 20.6 (-23.3 to 64.4) | 0.23 | |
INR | 26.4 (7.5 to 45.3) | 0.01b | |
aPTT | 0.5 (0.1 to 0.9) | 0.03b | |
Platelets | -0.1 (-0.1 to 0.0) | 0.08 | |
Positional changes | 1.9 (-1.7 to 5.4) | 0.27 | |
APACHE III | 0.2 (0.0 to 0.5) | 0.05 | |
Alarms | -2.3 (-4.6 to 0.0) | 0.05 |