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Table 5 Multivariate binary logistic regression analysis for acute kidney injury (AKI) development and mortality at all time points within 48 h of admission

From: Assessment of biochemical markers in the early post-burn period for predicting acute kidney injury and mortality in patients with major burn injury: comparison of serum creatinine, serum cystatin-C, plasma and urine neutrophil gelatinase-associated lipocalin

(a) Multivariate logistic regression analysis of AKI development

   

95% CI for odds ratio

 

Odds ratio

P -value

Lower

Upper

Age >60 years

  

3.107

12.117

TBSA burned >50%

8.628

0.000*

5.036

14.783

Sex, female

4.199

0.000*

1.940

9.086

Inhalation injury present

3.129

0.000*

1.734

5.647

Serum creatinine >1.1 mg/dL

74.930

0.000*

7.926

708.331

Serum cystatin C >1.1 mg/L

0.150

0.038*

0.025

0.902

Plasma NGAL >153 ng/mL

1.924

0.016*

1.128

3.282

Urine NGAL >131 ng/mL

2.568

0.009*

1.263

5.220

(b) Multivariate logistic regression analysis of mortality

   

95% CI for odds ratio

 

Odds ratio

P -value

Lower

Upper

Age >60 years

23.322

0.000*

9.885

55.023

TBSA burned >50%

25.821

0.000*

12.037

55.389

Sex, female

4.704

0.000*

1.999

11.070

Inhalation injury present

0.923

0.771

0.536

1.588

Serum creatinine >1.1 mg/dL

0.976

0.947

0.480

1.986

Serum cystatin C >1.1 mg/L

2.562

0.137

0.741

8.853

Plasma NGAL >153 ng/mL

1.886

0.023*

1.091

3.259

Urine NGAL >131 ng/mL

7.854

0.000*

3.949

15.622

  1. The biomarker cut-off values were designated according to normal reference ranges, regardless of our results. The model was based on the univariate analysis, and no significant interactions between correlated variables were found in a correlation matrix. *Statistically significant difference (P < 0.05).