Table 4 Performance characteristics of biochemical markers for predicting mortality

AUC of serum creatinine

0.699*

0.697*

0.747*

0.960*

0.941*

0.946*

 Cut-off value, mg/dL

0.85

0.85

0.85

1.15

1.65

0.95

 Sensitivity

0.588

0.529

0.625

0.923

0.889

1.000

 Specificity

0.640

0.640

0.694

0.898

0.980

0.776

AUC of serum cystatin C

0.636

0.501

0.581

0.812*

0.757*

0.811*

 Cut-off value(mg/L)

0.80

0.81

0.79

 Sensitivity

0.692

0.667

0.750

 Specificity

0.694

0.735

0.714

AUC of plasma NGAL

0.848*

0.919*

0.920*

0.892*

0.804*

0.776

 Cut-off value, ng/mL

144.5

191.5

181.0

177.0

185.5

 Sensitivity

0.824

0.882

0.938

0.923

0.778

 Specificity

0.760

0.820

0.837

0.702

0.735

AUC of urine NGAL

0.953*

0.984*

0.967*

0.940*

0.972*

0.939*

 Cut-off value, ng/mL

98.9

172.0

45.5

46.0

50.0

83.8

 Sensitivity

0.941

0.941

1.000

1.000

1.000

1.000

 Specificity

0.840

0.920

0.878

0.796

0.878

0.796

(b) Performance characteristics of biochemical markers for predicting late death (n = 73)

Time from admission

0 h

3 h

6 h

12 h

24 h

48 h

AUC of serum creatinine

0.595

0.561

0.609

0.625

0.594

0.617

AUC of serum cystatin C

0.478

0.450

0.529

0.503

0.463

0.425

AUC of plasma NGAL

0.650*

0.765*

0.800*

0.629

0.534

0.515

 Cut-off value. ng/mL

100.5

126.5

146.5

 Sensitivity

0.696

0.739

0.783

 Specificity

0.600

0.700

0.714

AUC of urine NGAL

0.734*

0.691*

0.717*

0.607

0.635

0.583

 Cut-off value, ng/mL

20.1

16.7

15.6

 Sensitivity

0.696

0.696

0.739

 Specificity

0.640

0.640

0.673