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Table 1 Patient characteristics according to acute kidney injury (AKI) development

From: Assessment of biochemical markers in the early post-burn period for predicting acute kidney injury and mortality in patients with major burn injury: comparison of serum creatinine, serum cystatin-C, plasma and urine neutrophil gelatinase-associated lipocalin

 

Non-AKI (n = 35)

AKI (n = 55)

P-value

  

Early AKI (n = 31)

Late AKI (n = 24)

 

Age, mean ± SD

45.4 ± 14.8

51.3 ± 15.5

52.5 ± 12.4

0.129

Sex, male:female, n (%)

29:6 (82:18)

28:3 (90:10)

20:4 (83:17)

0.641

Mode, FB:SB:EB:CB:SKB, n (%)

27:1:4:2:1 (77:3:12:5:3)

28:1:2:0:0 (91:3:6:0:0)

20:1:1:1:1 (84:4:4:4:4)

 

TBSA burned, %, mean ± SD

38.4 ± 14.1

70.7 ± 22.0

61.5 ± 19.2

<0.001

Third-degree burn wound, %, mean ± SD

24.6 ± 10.2

62.5 ± 28.6

48.5 ± 21.3

<0.001

Inhalation injury, n (%)

4 (11.4)

17 (54.8)

8 (33.3)

0.01

Mechanical ventilation, n (%)

5 (14.3)

28 (90.3)

19 (79.2)

<0.001

Rhabdomyolysis, n (%)

7 (20.0)

24 (77.4)

4 (16.7)

<0.001

Early vasopressor, n (%)

1 (2.8)

21 (67.7)

3 (12.5)

<0.001

Post-burn day of AKI, days, mean ± SD

 

1.2 ± 0.6

18.9 ± 12.1

<0.001

CRRT, n (%)

 

7 (22.6)

15 (62.5)

<0.001

Duration of CRRT, days, mean ± SD

 

1.9 ± 0.7

10.9 ± 2.8

<0.001

Sepsis, n (%)

3 (8.6)

7 (22.6)

20 (83.8)

<0.001

LOS, day, mean ± SD

55.7 ± 23.1

26.6 ± 43.6

42.2 ± 35.2

0.003

Mortality, n (%)

2 (5.7)

24 (77.4)

14 (58.3)

<0.001

Maximal RIFLE score, n (R:I:F)

 

0:10:21

1:5:18

 
  1. Early AKI, AKI that developed within 5 days of injury; Late AKI, AKI that developed after 5 days post injury; FB, flame burn; SB, scalding burn; EB, electrical burn; CB, chemical burn; SKB, spark burn; TBSA, total body surface area; Early vasopressor, vasopressor infusion due to shock within 1 day of admission; CRRT, continuous renal replacement therapy; LOS, length of hospital stay; RIFLE, risk, injury, failure, sustained loss, and end-stage kidney disease; n, number of patients.