Categories | Non-etomidate group | Etomidate group | P value |
---|---|---|---|
Number of patients | 1,279 | 1,775 | Â |
CRP, mg/L | Â | Â | Â |
 Missing | 140 (10.9%) | 80 (4.5%) |  |
 Day 1 | 76.9 ± 1.2 | 77.0 ± 1.0 | 0.924 |
 Day 2 | 183.8 ± 2.6 | 194.1 ± 2.2 | 0.382 |
 Day 3 | 205.9 ± 3.8 | 211.5 ± 3.4 | 0.316 |
 Day 4 | 189.7 ± 4.9 | 187.9 ± 4.3 | 0.340 |
 Day 5 | 166.6 ± 6.5 | 150.9 ± 4.9 | 0.306 |
PCT, ng/mL | Â | Â | Â |
 Missing | 732 (57.2%) | 963 (54.2%) |  |
 Day 1 | 4.1 ± 0.4 | 5.6 ± 0.5 | 0.053 |
 Day 2 | 8.4 ± 0.9 | 10.0 ± 1.1 | 0.090 |
 Day 3 | 7.9 ± 0.9 | 8.8 ± 0.9 | 0.312 |
 Day 4 | 6.3 ± 0.9 | 6.6 ± 0.9 | 0.673 |
 Day 5 | 4.7 ± 0.6 | 5.7 ± 0.7 | 0.254 |
Leukocytes, 103/μL |  |  |  |
 Missing | 73 (5.7%) | 63 (3.5%) |  |
 Day 1 | 12.8 ± 0.2 | 11.7 ± 0.1 | 0.061 |
 Day 2 | 11.9 ± 0.2 | 11.7 ± 0.2 | 0.327 |
 Day 3 | 11.9 ± 0.3 | 11.7 ± 0.3 | 0.899 |
 Day 4 | 11.5 ± 0.4 | 11.3 ± 0.4 | 0.969 |
 Day 5 | 11.7 ± 0.5 | 11.3 ± 0.4 | 0.776 |
CK | Â | Â | Â |
 U/L | 1347 ± 71 | 1642 ± 86 | 0.002 |
 Missing | 390 (30.5%) | 226 (12.7%) |  |
CK-MB | Â | Â | Â |
 U/L | 10.1 ± 0.2 | 10.0 ± 0.2 | 0.801 |
 Missing | 444 (34.7%) | 292 (16.4%) |  |
Troponin | Â | Â | Â |
 μg/L | 9.8 ± 0.6 | 11.5 ± 0.5 | 0.004 |
 Missing | 391 (30.5%) | 230 (12.9%) |  |
Hemodialysis | Â | Â | Â |
 N | 8.8% | 10.2% | 0.190 |
 Hours | 105 ± 12 | 112 ± 10 | 0.861 |
SOFA score | Â | Â | Â |
 Missing | 655 (51.2%) | 884 (49.8%) |  |
 Day 1 | 7.9 ± 0.1 | 7.9 ± 0.1 | 0.340 |
 Day 2 | 7.2 ± 0.2 | 7.3 ± 0.1 | 0.122 |
 Day 3 | 7.4 ± 0.2 | 7.3 ± 0.2 | 0.697 |
 Day 4 | 8.3 ± 0.3 | 8.2 ± 0.2 | 0.859 |
 Day 5 | 8.8 ± 0.3 | 8.4 ± 0.3 | 0.394 |
Hospital days | 17.4 ± 0.6 | 18.7 (0.6%) | 0.250 |
ICU days | 2.5 ± 0.1 | 2.6 ± 0.1 | 0.857 |
ICU discharge | Â | Â | Â |
 Day 1 | 694 (56%) | 883 (51%) | 0.013 |
 Day 2 | 158 (13%) (∑852; 68%) | 297 (17%) (∑1180; 68%) | 0.937 |
 Day 3 | 151 (12%) (∑1003; 80%) | 205 (12%) (∑1385; 80%) | 0.795 |
 Day 4 | 80 (6%) (∑1083; 87%) | 115 (7%) (∑1500; 87%) | 0.898 |
 Day 5 | 39 (3%) (∑1122; 90%) | 51 (3%) (∑1551; 90%) | 0.776 |
ICU re-admission | 70 (5.5%) | 102 (5.8%) | 0.746 |
7-day mortality | 39 (3.0%) | 64 (3.6%) | 0.401 |
30-day mortality | 66 (5.2%) | 106 (6.0%) | 0.337 |
Overall in hospital mortality | 82 (6.4%) | 121(6.8) | 0.657 |