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Table 4 Postoperative data of the two study groups

From: Comparison of clinical outcome variables in patients with and without etomidate-facilitated anesthesia induction ahead of major cardiac surgery: a retrospective analysis

Categories

Non-etomidate group

Etomidate group

P value

Number of patients

1,279

1,775

 

CRP, mg/L

   

 Missing

140 (10.9%)

80 (4.5%)

 

 Day 1

76.9 ± 1.2

77.0 ± 1.0

0.924

 Day 2

183.8 ± 2.6

194.1 ± 2.2

0.382

 Day 3

205.9 ± 3.8

211.5 ± 3.4

0.316

 Day 4

189.7 ± 4.9

187.9 ± 4.3

0.340

 Day 5

166.6 ± 6.5

150.9 ± 4.9

0.306

PCT, ng/mL

   

 Missing

732 (57.2%)

963 (54.2%)

 

 Day 1

4.1 ± 0.4

5.6 ± 0.5

0.053

 Day 2

8.4 ± 0.9

10.0 ± 1.1

0.090

 Day 3

7.9 ± 0.9

8.8 ± 0.9

0.312

 Day 4

6.3 ± 0.9

6.6 ± 0.9

0.673

 Day 5

4.7 ± 0.6

5.7 ± 0.7

0.254

Leukocytes, 103/μL

   

 Missing

73 (5.7%)

63 (3.5%)

 

 Day 1

12.8 ± 0.2

11.7 ± 0.1

0.061

 Day 2

11.9 ± 0.2

11.7 ± 0.2

0.327

 Day 3

11.9 ± 0.3

11.7 ± 0.3

0.899

 Day 4

11.5 ± 0.4

11.3 ± 0.4

0.969

 Day 5

11.7 ± 0.5

11.3 ± 0.4

0.776

CK

   

 U/L

1347 ± 71

1642 ± 86

0.002

 Missing

390 (30.5%)

226 (12.7%)

 

CK-MB

   

 U/L

10.1 ± 0.2

10.0 ± 0.2

0.801

 Missing

444 (34.7%)

292 (16.4%)

 

Troponin

   

 μg/L

9.8 ± 0.6

11.5 ± 0.5

0.004

 Missing

391 (30.5%)

230 (12.9%)

 

Hemodialysis

   

 N

8.8%

10.2%

0.190

 Hours

105 ± 12

112 ± 10

0.861

SOFA score

   

 Missing

655 (51.2%)

884 (49.8%)

 

 Day 1

7.9 ± 0.1

7.9 ± 0.1

0.340

 Day 2

7.2 ± 0.2

7.3 ± 0.1

0.122

 Day 3

7.4 ± 0.2

7.3 ± 0.2

0.697

 Day 4

8.3 ± 0.3

8.2 ± 0.2

0.859

 Day 5

8.8 ± 0.3

8.4 ± 0.3

0.394

Hospital days

17.4 ± 0.6

18.7 (0.6%)

0.250

ICU days

2.5 ± 0.1

2.6 ± 0.1

0.857

ICU discharge

   

 Day 1

694 (56%)

883 (51%)

0.013

 Day 2

158 (13%) (∑852; 68%)

297 (17%) (∑1180; 68%)

0.937

 Day 3

151 (12%) (∑1003; 80%)

205 (12%) (∑1385; 80%)

0.795

 Day 4

80 (6%) (∑1083; 87%)

115 (7%) (∑1500; 87%)

0.898

 Day 5

39 (3%) (∑1122; 90%)

51 (3%) (∑1551; 90%)

0.776

ICU re-admission

70 (5.5%)

102 (5.8%)

0.746

7-day mortality

39 (3.0%)

64 (3.6%)

0.401

30-day mortality

66 (5.2%)

106 (6.0%)

0.337

Overall in hospital mortality

82 (6.4%)

121(6.8)

0.657

  1. Continuous variables are given as mean ± standard error, and categorical variables are presented as number (percentage). CK, creatinkinasis; CML, Cormack and Lehane; CRP, C-reactive protein; ICU, intensive care unit; PCT, procalcitonine; SOFA, Sequential Organ Failure Assessment.