Outcome prediction in sepsis: Speckle tracking echocardiography based assessment of myocardial function

Table 1 Baseline physiological and clinical data with comparison for survival at 30 days and 6 months

Characteristic	Baseline	30-day mortality		6-month mortality
Characteristic	Baseline	Survivors	Nonsurvivors	Survivors	Nonsurvivors
Mortality	60	40 (67%)	20 (33%)	31 (52%)	29 (48%)
Physiology
Age (years)	62 ± 15	60 ± 16	65 ± 13	60 ± 17	65 ± 13
Female (%)	50	30	20	21.7	28.3
SOFA score	11 ± 4	10 ± 4*	13 ± 3*	10 ± 4*	12 ± 4*
MAP (mmHg)	62 ± 13	63 ± 15	60 ± 8	63 ± 13	61 ± 61
Hemoglobin (g/dl)	10.1 ± 1.6	10.2 ± 1.6	9.8 ± 1.6	10.4 ± 1.6	9.7 ± 1.5
NE dose (μg/kg/minute)	0.2 (0.06 to 0.34)	0.15 (0.04 to 0.475)	0.225 (0.08 to 0.32)	0.18 (0.07 to 0.5)	0.2 (0.1 to 0.3)
Vasopressin (u/minute)	0.04 (0.03 to 0.04)	0.04 (0.03 to 0.04)	0.04 (0.03 to 0.04)	0.04 (0.03 to 0.04)	0.04 (0.03 to 0.04)
ScvO₂ (%)	72 ± 11	70 ± 13	75 ± 8	72 ± 11	72 ± 12
PaO₂/FiO₂ (mmHg)	195 (128 to 290)	247 (153 to 310)*	163.5 (113 to 199)*	248.5 (76 to 300)	175 (124 to 260)
pCO₂ (mmHg)	40 ± 12	38 ± 9*	45 ± 14*	38 ± 11	43 ± 2
pH	7.29 ± 0.1	7.3 ± 0.1	7.27 ± 0.1	7.3 ± 0.1	7.29 ± 0.1
Lactate (mmol/l)	3 ± 2.8	2.4 ± 0.4*	4.2 ± 0.6*	1.45 (1 to 3.78)	2.4 (1.4 to 4.2)
Creatinine (mg/dl)	1.9 ± 1	2.1 ± 1.2	1.6 ± 0.7	1.84 ± 0.9	2 ± 1.2
Troponin T (ng/ml)	0.03 (0.01 to 0.16)	0.03 (0.01 to 0.2)	0.03 (0.01 to 0.12)	0.025 (0.01 to 0.2)	0.03 (0.01 to 0.1)
Clinical
Respiratory issues	18 (30%)	12	6	7	11
Coronary artery disease	8 (13%)	7	1	3	5
Chronic renal failure	7 (12%)	5	2	4	3
Acute kidney injury	25 (42%)	17	8	12	13
Mechanical ventilation	39 (65%)	21*	18*	15*	24*

Data presented as n (%), mean ± standard deviation or median (interquartile range). * P <0.05 by analysis of variance. MAP, mean arterial pressure; NE, noradrenaline; pCO₂, partial pressure of carbon dioxide; PaO₂/FiO₂, arterial partial pressure of oxygen/fraction of inspired oxygen ratio; ScvO₂, central venous oxygen saturation; SOFA, Sequential Organ Failure Assessment.

ISSN: 1364-8535