Number (percentage) of linezolid patients | ||||||
---|---|---|---|---|---|---|
Patient groups, number of patients | AUC24, mg*h/La | Cmin, mg/Lb | ||||
<200 | 200 to 400 | >400 | <2 | 2 to 10 | >10 | |
Total patients, n =30 | 19 (63) | 9 (30) | 2 (7) | 15 (50) | 13 (43) | 2 (7) |
Male patients, n = 20c | 13 (65) | 5 (25) | 2 (10) | 11 (55) | 7 (35) | 2 (10) |
Female patients, n = 10 | 6 (60) | 4 (40) | 4 (40) | 6 (60) | ||
On CRRT, n = 5d | 2 (40) | 1 (20) | 2 (40) | 3 (60) | 2 (40) | |
Not on CRRT, n = 25 | 17 (68) | 8 (32) | 15 (60) | 10 (40) | ||
On ECLA, n = 7c | 5 (71) | 2 (29) | 5 (71) | 2 (29) | ||
Not on ECLA, n = 23 | 14 (61) | 7 (30) | 2 (9) | 10 (43) | 11 (48) | 2 (9) |
After liver transplantation, n = 5f | 2 (40) | 1 (20) | 2 (40) | 3 (60) | 2 (40) | |
After lung transplantation, n = 10c | 6 (60) | 4 (40) | 6 (60) | 4 (40) | ||
No transplantation, n = 15 | 11 (73) | 4 (27) | 9 (60) | 6 (40) |