Endogenous thrombin potential following hemostatic therapy with 4-factor prothrombin complex concentrate: a 7-day observational study of trauma patients

Table 3 Blood transfusion and hemostatic therapy during the first 24 hours after hospital admission

	NCT group	FC group	FC-PCC group	P-value
RBC, U	0 (0 to 2)	3 (0 to 5)	8 (6 to 10.5)	<0.0001
FFP, U	0 (0 to 0)	0 (0 to 0)	0 (0 to 0)	ns
Platelet concentrate, U	0 (0 to 0)	0 (0 to 0)	0 (0 to 1)	<0.0001
Fibrinogen concentrate, g	0 (0 to 0)	3 (3 to 5)	8 (5 to 11)	0.0002
PCC, IU	0 (0 to 0)	0 (0 to 0)	2,400 (1,650 to 2,500)	nc

RBC, red blood cells; FFP, fresh frozen plasma; nc, not calculated; ns, not significant; PCC, prothrombin complex concentrate; NCT group, no coagulation therapy; FC group, fibrinogen concentrate only; FC-PCC group, prothrombin complex concentrate and fibrinogen concentrate. Data are presented as median (interquartile range). P-values are derived from the Kruskal-Wallis test; significance level P <0.05.

ISSN: 1364-8535