Table 1 Major characteristics of patients
Characteristic | Cases | Controls | P value |
|---|---|---|---|
(n = 43) | (n = 67) | (two-tailed) | |
Age (years) | 61.0 (50.0 to 72.5) | 60.5 (49.5 to 70.0) | 0.76 |
Sex ratio (male/female) | 2.9 | 2.3 | 0.67 |
Simplify Acute Physiology Score | 51.5 | 53.0 | 0.23 |
Surgical patient | 37.2 | 20.3 | 0.07 |
Abdominal surgery | 30.2 | 10.5 | 0.01 |
Other surgery | 7.0 | 10.5 | 0.7 |
Deep venous catheter | 97.7 | 96.8 | 1 |
Broad-spectrum antibiotherapy | 100 | 98.4 | 1 |
Corticoids | 30.2 | 39.7 | 0.41 |
Vasopressor therapy | 65.1 | 57.8 | 0.55 |
Exclusive parenteral nutrition | 37.2 | 4.7 | <5 × 10-5 |
Extrarenal epuration | 62.8 | 29.7 | 0.001 |
Mechanical invasive ventilation | 100 | 98.4 | 1 |
Duration of mechanical ventilation (days) | 31.5 (14.0 to 47.0) | 28.5 (15.5 to 42.0) | 0.5 |
Neutropaenia | 7.0 | 6.4 | 1 |
Antifungal therapy | 86.0 | 18.0 | <5 × 10-5 |
Fluconazole | 59.5 | 54.5 | |
Voriconazole | 13.5 | 0 | |
Caspofungin | 54.1 | 54.6 | |
Liposomal amphotericin-B | 5.4 | 9.1 | |
5-Fluorocytosine | 2.7 | 0 | |
Bacteraemia | 58.1 | 27.0 | 0.002 |
Distribution of bacteria | |||
Gram-positive | 28.0 | 18.8 | |
Gram-negative | 56.0 | 56.2 | |
Mixed Gram-positive and Gram-negative | 16.0 | 25.0 | |
ICU duration of hospitalisation | 33.5 (23.5 to 60.0) | 29.0 (19.5 to 46.5) | 0.5 |
ICU mortality | 62.8 | 38.5 | 0.02 |
Hospital mortality | 65.1 | 44.6 | 0.05 |