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Table 3 Differences and similarities between cerebral sodium wasting and syndrome of inappropriate antidiuretic hormone

From: Brain–kidney crosstalk

 

Cerebral sodium wasting

Syndrome of inappropriate antidiuretic hormone

Extracellular volume

Normal or ↑

Urine sodium concentration

Normal or ↑

Normal or ↑

Plasma renin

± ↑

± ↓

Plasma aldosterone

± ↓

Serum urate

↓↓

↓ or normal

Fractional excretion urate

↑↑

↑ or normal

Fractional excretion phosphate

± ↑

Normal

  1. ↓, decreased; ↑, increased; ↓↓, greatly decreased; ↑↑, greatly increased.