Table 3 Levels of 33 cytokines showing no significant difference between mild or moderately severe and severe acute pancreatitis a
From: Circulating cytokines in predicting development of severe acute pancreatitis
Cytokines | Mild or moderately severe AP (n= 138) | P- valueb | Severe AP (n= 25) |
|---|---|---|---|
CTACK | 993.1 (746.4 to 1,556.1) | 0.033 (NS) | 693.3 (652.5 to 1,150.6) |
Eotaxinc | 1 (0 to 1) | 0.133 (NS) | 1 (0 to 1) |
FGF | 25.9 (8.6 to 44.6) | 0.123 (NS) | 19.4 (0.4 to 35.2) |
GM-CSFc | 0 (0) | 0.663 (NS) | 0 (0 to 1) |
IFN-γ | 99.5 (50.7 to 151.0) | 0.772 (NS) | 82.4 (50.9 to 149.5) |
IP-10 | 379.3 (244.5 to 594.0) | 0.475 (NS) | 446.2 (222.6 to 825.3) |
IL-1αc | 0 (0 to 1) | 0.473 (NS) | 1 (0 to 1) |
IL-1β | 1.9 (0.8 to 3.0) | 0.961 (NS) | 1.9 (0.5 to 3.4) |
IL-1Ra | 121.1 (64.8 to 260.0) | 0.131 (NS) | 202.6 (70.9 to 669.8) |
IL-2 | 7.6 (2.2 to 13.4) | 0.796 (NS) | 6 to 7 (1.7 to 12.9) |
IL-3c | 0 (0) | 0.008 (NS) | 0 (0 to 1) |
IL-4 | 5.1 (2.6 to 7.5) | 0.261 (NS) | 3.8 (2.3 to 6.4) |
IL-5 | 2.7 (1.6 to 4.1) | 0.091 (NS) | 1.8 (1.0 to 3.4) |
IL-7 | 5.9 (3.9 to 10.5) | 0.482 (NS) | 5.2 (3.9 to 9.4) |
IL-9 | 19.5 (7.3 to 37.8) | 0.410 (NS) | 16.1 (1.7 to 38.7) |
IL-10 | 8.2 (3.9 to 17.7) | 0.012 (NS) | 15.8 (6.2 to 42.3) |
IL-12p70 | 18.7 (11.2 to 40.4) | 0.442 (NS) | 15.5 (9.0 to 36.5) |
IL-12p40c | 0 (0) | 0.691 (NS) | 0 (0) |
IL-13 | 7.2 (3.9 to 13.5) | 0.249 (NS) | 6.5 (2.6 to 12.1) |
IL-15c | 0 (0) | 0.018 (NS) | 0 (0 to 1) |
IL-16 | 220.2 (99.9 to 786.8) | 0.120 (NS) | 341.3 (157.2 to 980.1) |
IL-17A | 79.8 (33.2 to 155.9) | 0.084 (NS) | 45.8 (9.2 to 98.4) |
MIP-1α | 6.2 (3.7 to 8.0) | 0.215 (NS) | 4.6 (2.4 to 7.1) |
MIP-1β | 67.1 (42.6 to 90.2) | 0.830 (NS) | 63.6 (40.1 to 95.8) |
MIF | 695.8 (348.5 to 1,553.9) | 0.004 (NS) | 1461.2 (713.4 to 4,529.4) |
MIG | 1,415.5 (821.0 to 2,348.2) | 0.021 (NS) | 2,147.5 (1,257.4 to 4,268.7) |
PDGF-BB | 1,183.6 (360.4 to 2,475.2) | 0.063 (NS) | 583.3 (207.8 to 1,427.3) |
RANTES | 2,905.6 (1,110.3 to 4,511.1) | 0.093 (NS) | 1,877.2 (787.5 to 3,090.9) |
SCGF-β | 31452.4 (21610.3 to 46978.0) | 0.004 (NS) | 47129.9 (30743.1 to 56343.2) |
TRAIL | 57.4 (33.3 to 92.0) | 0.042 (NS) | 84.8 (51.8 to 122.7) |
TNF-α | 20.8 (10.3 to 31.9) | 0.730 (NS) | 18.2 (9.7 to 31.5) |
TNF-βc | 0 (0 to 1) | 0.187 (NS) | 0 (0) |
VEGF | 29.9 (17.7 to 71.1) | 0.436 (NS) | 23.6 (17.4 to 64.2) |