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Table 1 Demographic and etiology

From: Is pentobarbital safe and efficacious in the treatment of super-refractory status epilepticus: a cohort study

 

SRSE n = 31

RSE n = 116

Odds ratio (95% CI)

P-value

Age, years1

48 (+/-20)

61 (+/-17)

0.96 (0.94, 0.98)

0.001*

Women, n (%)

17 (55)

78 (67)

  

Race, n (%)

    

White

15 (48)

52 (45)

-

-

Non white

16 (52)

64 (55)

-

-

History of epilepsy, n (%)

8 (26)

38 (33)

  

Etiology, n (%)

    

Acute

16 (52)

70 (60)

-

-

  Encephalitis

12 (35)

13 (11)

4.35 (1.7, 11.09)

0.002*

  Intracerebral hemorrhage

1 (3)

31 (27)

0.09 (0.011, 0.69)

0.021

  Stroke

1 (3)

4 (3)

  

  Toxic-metabolic

1 (3)

11 (9)

  

  Traumatic brain injury

1 (3)

11 (9)

  

Progressive

10 (30)

35 (30)

-

-

  Neoplasia

4 (10)

7 (6)

  

  Degenerative

1 (3)

6 (5)

  

Epilepsy

5 (16)

22 (19)

  

Idiopathic/cryptogenic

5 (16)

11 (9)

  

Catastrophic etiology, n (%)

8 (26)

NA

-

-

Length of SE, days2

6.5 (4, 11)

NA

-

-

Type of SE, n (%)

    

Convulsive SE

23 (74)

66 (57)

  

NCSE

8 (26)

50 (43)

  
  1. Data are given as number (n) (%), 1mean (+/- SD), or 2median (IQR). Catastrophic etiology is defined as life expectancy due to underlying etiology less than 90 days. The odds ratio for encephalitis associated with SRSE was 2.91 (1.08, 7.85) after correcting for age. *Age and encephalitis were independently associated with SRSE. NCSE, non-convulsive status epilepticus; SE, status epilepticus; RSE, refractory status epilepticus; SRSE, super-refractory status epilepticus; NA, not applicable.
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Critical Care

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