Table 4 Principal respiratory outcomes in nonrandomised studies
Study | Time | PaCO2change (mmHg) | Change in PaO2/FiO2(mmHg) | Pplat change (mmHg) | Vtreduction | pH change |
|---|---|---|---|---|---|---|
Forster and colleagues [25] | 4 hours | 68.00 ± 8.28 to 49.6 ± 6.18 | NR | 19.8 ± 2.0 to 19.0 ± 2.4 | 8.41 ± 0.30 to 8.34 ± 1.04 | 7.18 ± 0.08 to 7.30 ± 0.07 |
Nierhaus and colleagues [29] | Day 1 | 80.0 ± 23.0 to 54.0 ± 19.0 | 100.0 ± 28.9 to 120.7 ± 51.2 | 34.0 ± 3.0b to 28.3 ± 4.0 | 292.5 ± 94.0a to 183.0 ± 67.0 | 7.18 ± 0.22 to 7.37 ± 0.09 |
Weber-Carstens and colleagues [26] | NR | 120 (81.9 to 152.5) to 60.3 (52.5 to 69) | 121.5 (79.3 to 178.3) to 87 (73 to 139.3) | 39 (34.8 to 43.3) to 31.5 (28.8 to 33.5) | 5.2 (4.4 to 5.9) to 3.5 (3.1 to 4.3)b | 7.06 (6.9 to 7.3) to 7.38 (7.18 to 7.48) |
Zimmermann and colleagues [20] | 24Â hours | 73 (61 to 86) to 41 (34 to 48) | 75 (62 to 130) to 110 (86 to 160) | 35 (31 to 38) to 30 (26 to 34) | 6.6 (5.3 to 7.2) to 4.4 (3.4 to 5.4)b | 7.23 (7.16 to 7.30) to 7.44 (7.37 to 7.45) |
Terragni and colleagues [21] | NR | 47.2 ± 8.6 to 73.6 ± 11.1 | NR | NR | NR | 7.20 ± 0.02 to 7.38 ± 0.04 |
Muellenbach and colleagues [27] | 12Â hours | 65.26 (54 to 72) to 39.8 (36 to 42) | 61.6 (47.3 to 85.6) to 135.8 (87.8 to 153) | NR | 450 (400 to 542.5) to 200 (145 to 250)a | 7.25 (7.22 to 7.29) to 7.4 (7.37 to 7.42) |
Bein and colleagues [28] | 24Â hours | 60 (48 to 80) to 34 (30 to 39) | 58 (47 to 78) to 107 (74 to 142) | NR | 430 (360 to 540) to 380 (320 to 470)a | 7.27 (7.18 to 7.36) to 7.45 (7.41 to 7.50) |
Liebold and colleagues [30] | 24 hours | 59 ± 17 to 32 ± 8 | 50 to 110 | NR | NR | NR |
Guinard and colleagues [22] | NR | NR | NR | NR | NR | NR |
Brunet and colleagues [23] | NR | 66 ± 25 to 43 ± 6 | 79 ± 21 to 207 ± 108 | 48 ± 10 to 37 ± 5 | 622 ± 131 to 270 ± 60a | NR |
Bindslev and colleagues [31] | NR | NR | NR | NR | NR | NR |
Gattinoni and colleagues [24] | NR | NR | NR | NR | NR | NR |