Figure 1From: Time from admission to initiation of surgery for source control is a critical determinant of survival in patients with gastrointestinal perforation with associated septic shockProtocol for gastrointestinal perforation with associated septic shock. The protocol for early infectious source control (EISC) and early goal-directed therapy (EGDT) for gastrointestinal perforation with septic shock was implemented at Nihon University Itabashi Hospital. GI, gastrointestinal; SIRS: systemic inflammatory response syndrome; IVF, intravenous fluids; CVP, central venous pressure; MAP, mean arterial pressure; ScvO2, central venous oxygen saturation. Revised points from the original protocol of Rivers et al. [3]; *in mechanical ventilation control, the target CVP is ≥8 mm Hg; **the original protocol specified dobutamine, but this was not used; ***blood gas analysis (BGA) measurement of ScvO2 in blood drawn from the internal jugular vein via an indwelling catheter.Back to article page