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Table 1 Patients with suspected VAP

From: Impact of prior statin therapy on the outcome of patients with suspected ventilator-associated pneumonia: an observational study

 

Overall

Statin previous users

Statin-naive patients

P

(n = 349)

(n = 93)

(n = 256)

Age (years)

64.0 (17.0-94.0)

68.0 (27.0-90.0)

63.0 (17.0-94.0)

<0.01

SAPS II

50.0 (6.0-109.0)

54.0 (18.0-109.0)

49.0 (6.0-99.0))

0.06

Gender, male (n (%))

254 (72.8)

80 (86.0)

174 (68.0)

<0.01

Hospitalization prior to ICU admission (n (%))

347 (62.3)

89 (67.9)

258 (60.6)

0.14

Underlying disease(s)

 COPD (n (%))

99 (17.7)

33 (25.1)

66 (15.5)

0.01

 Chronic renal failure (n (%))

23 (6.6)

10 (10.9)

13 (5.1)

0.05

 Chronic cardiac disease (n (%))

138 (39.6)

65 (70.6)

73 (28.5)

<0.01

 Diabetes mellitus (n (%))

67 (19.2)

29 (31.5)

38 (14.8)

<0.01

 Cirrhosis (n (%))

17 (4.9)

2 (2.2)

15 (5.9)

0.16

Immunosuppression (excepting steroids) (n (%))

17 (4.9)

4 (4.3)

13 (5.1)

0.78

 Steroids (n (%))

20 (5.8)

8 (8.7)

12 (4.7)

0.16

 Cancer (n (%))

31 (8.9)

10 (10.9)

21 (8.2)

0.44

Nursing-home resident (n (%))

16 (4.6)

2 (2.1)

14 (5.5)

0.19

Main admission diagnosis

   

0.20

 Respiratory distress (n (%))

133 (38.1)

33 (35.5)

100 (39.1)

0.54

 Extrapulmonary sepsis (n (%))

107 (30.6)

33 (35.5)

74 (69.2)

0.24

 Neurologic failure (n (%))

50 (14.3)

10 (10.7)

40 (15.6)

0.24

 Abdominal surgery (n (%))

17 (4.9)

2 (2.1)

15 (5.8)

0.15

 Miscellaneous (n (%))

42 (12.0)

15 (16.1)

27 (10.5)

0.16

  1. Baseline characteristics according to statin exposure. VAP, ventilator-associated pneumonia; SAPS II, simplified acute physiology score II; ICU, intensive care unit; COPD, chronic obstructive pulmonary disease; MV, mechanical ventilation.