Risk stratification and prognostic performance of the predisposition, infection, response, and organ dysfunction (PIRO) scoring system in septic patients in the emergency department: a cohort study

Table 4 Areas under the receiver operating characteristic curves of predictors

Outcome variable	Predictor	AUC	SE	P value	95% CI for AUC
					5%	95%
ICU admission	PIRO	0.889	0.017	0.000	0.855	0.923
	Predisposition	0.570	0.026	0.009	0.520	0.621
	Infection	0.528	0.026	0.299	0.477	0.579
	Response	0.606	0.028	0.000	0.551	0.660
	Organ dysfunction	0.888	0.017	0.000	0.856	0.921
	MEDS	0.774**	0.022	0.000	0.731	0.817
	APACHE II	0.789**	0.020	0.000	0.750	0.829
MOD	PIRO	0.817	0.017	0.000	0.785	0.849
	Predisposition	0.594	0.022	0.000	0.550	0.638
	Infection	0.536	0.023	0.127	0.491	0.580
	Response	0.487	0.025	0.573	0.438	0.536
	Organ dysfunction	0.851	0.015	0.000	0.821	0.881
	MEDS	0.758*	0.019	0.000	0.721	0.796
	APACHE II	0.764*	0.019	0.000	0.727	0.801
28-day mortality	PIRO	0.744	0.022	0.000	0.701	0.786
	Predisposition	0.555	0.025	0.029	0.507	0.603
	Infection	0.507	0.025	0.795	0.457	0.556
	Response	0.427	0.027	0.004	0.374	0.481
	Organ dysfunction	0.816	0.019	0.000	0.780	0.852
	MEDS	0.736	0.022	0.000	0.693	0.779
	APACHE II	0.742	0.022	0.000	0.700	0.784

APACHE, Acute Physiology and Chronic Health Evaluation; AUC, area under the receiver operating characteristic curve; CI, confidence interval; MEDS, Mortality in Emergency Department Sepsis; MOD, multiple organ dysfunction; PIRO, predisposition, infection, response, and organ dysfunction; SE, standard error. Compared with PIRO: **P < 0.01; *P < 0.05.

ISSN: 1364-8535