Prediction of mortality in adult patients with severe acute lung failure receiving veno-venous extracorporeal membrane oxygenation: a prospective observational study

Table 2 Comparison of mortality prediction models in the study population (number = 304)

Model	Valid n	AUC	P- value^a	Hosmer-Lemeshow test P- value
Pre-ECMO prediction
SOFA score	303	0.611 (0.544-0.678)	0.027	<0.0001^b
ECMOnet score	280	0.604 (0.537-0.671)	0.009	0.0002^b
PRESERVE	289	0.685 (0.623-0.748)	0.12	0.004^b
Model 1	284	0.746 (0.689-0.804)	Reference	0.50
Day 1 prediction
Model 2	263	0.786 (0.730-0.843)	0.026	0.73

^aPairwise comparisons of AUCs with Model 1 using DeLongs method (n = 241) [12]. ^bModified Hosmer-Lemeshow test comparing grouped mortality risk against the deciles of Model 1 predictions. AUC, area under receiver operating characteristics curve; ECMO, extracorporeal membrane oxygenation; SOFA, Sequential Organ Failure Assessment.

ISSN: 1364-8535