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Table 1 Baseline characteristics of all 562 patients included in the study

From: Hemostasis during the early stages of trauma: comparison with disseminated intravascular coagulation

 

Non-DIC

JAAM DIC

P value

(n = 257)

ISTH (−) (n = 210)

ISTH (+) (n = 95)

Age (years)

48 ± 20

49 ± 23

49 ± 25

0.682

Sex (male/female)

64/193

76/134

43/52

0.001

Injury Severity Score

20.7 ± 11.5

25.7 ± 13.0

35.3 ± 13.0

0.000

APACHE II score

13.9 ± 7.2

19.7 ± 8.2

26.1 ± 8.1

0.000

SOFA score

5.0 ± 2.2

6.5 ± 3.3

10.2 ± 3.6

0.000

SIRS criteria

2.8 ± 0.8

3.4 ± 0.7

3.0 ± 0.9

0.000

JAAM DIC score (day 0)

1.5 ± 1.0

4.7 ± 1.0

6.7 ± 1.3

0.000

ISTH DIC score (day 0)

1.2 ± 1.2

3.3 ± 0.6

5.9 ± 1.0

0.000

MODS (yes/no)

2/255

22/188

41/54

0.000

Outcome (survived/died)

248/9

174/36

54/41

0.000

FDP/D-dimer ratio

1.6 ± 0.9

1.8 ± 0.7

4.3 ± 19.8

0.000

Lactate (mM)

3.2 ± 1.9

4.9 ± 3.2

8.2 ± 5.1

0.000

  1. APACHE, Acute Physiology and Chronic Health Evaluation; DIC, disseminated intravascular coagulation; FDP, fibrin fibrinogen degradation products; FFP, fresh frozen plasma; ISTH, International Society on Thrombosis and Haemostasis; JAAM, Japanese Association for Acute Medicine; MODS, multiple organ dysfunction syndrome; PRBCs, packed red blood cells; SIRS, systemic inflammatory response syndrome; SOFA, Sequential Organ Failure Assessment. ISTH (−) (+), JAAM DIC patients who did not meet the ISTH overt DIC criteria and those who simultaneously met the ISTH overt DIC criteria, respectively. P value, Kruskal-Wallis test.