|
Time point
|
pH
|
PaCO2
|
PaO2
|
HCO3-
|
BE
|
Lactate
|
|---|
|
Baseline
| | | | | | |
|
Control (n = 21)
|
7.37 ± 0.1
|
40 ± 13
|
98 ± 33
|
22.8 ± 4.9
|
-1.7 ± 5.6
|
1.4 ± 0.5
|
|
Lactate (n = 19)
|
7.40 ± 0.06
|
36 ± 9
|
103 ± 28
|
23.3 ± 3.3
|
-0.3 ± 4.1
|
2.4 ± 2.3
|
|
Post-bolus
| | | | | | |
|
Control (n = 21)
|
7.37 ± 0.09
|
40 ± 9
|
91 ± 19
|
23.1 ± 5.1
|
-1.01 ± 5.7
|
2 ± 1.4
|
|
Lactate (n = 19)
|
7.45 ± 0.05b,c
|
38 ± 8
|
95 ± 30
|
25.9 ± 4.1b
|
2.7 ± 4.2
|
4.8 ± 2.0b
|
|
6 hours
| | | | | | |
|
Control (n = 20)
|
7.38 ± 0.06
|
42 ± 9
|
93 ± 27
|
24.1 ± 4.8
|
-0.7 ± 5.3
|
1.6 ± 1.2
|
|
Lactate (n = 19)
|
7.49 ± 0.04b,c
|
43 ± 5b
|
87 ± 24
|
32.5 ± 4.8b,c
|
8.9 ± 4.5b,c
|
2.9 ± 1.0c
|
|
12 hours
| | | | | | |
|
Control (n = 19)
|
7.38 ± 0.07
|
42 ± 10
|
95 ± 37
|
24.3 ± 4.7
|
-0.2 ± 5.2
|
1.4 ± 0.6
|
|
Lactate (n = 19)
|
7.51 ± 0.04b,c
|
47 ± 5b
|
82 ± 24
|
37.1 ± 5.3b,c
|
12.9 ± 4.6
|
3.1 ± 1.6c
|
|
24 hours
| | | | | | |
|
Control (n = 19)
|
7.41 ± 0.07
|
38 ± 11
|
84 ± 20
|
23.9 ± 5.4
|
-0.9 ± 5.8
|
1.5 ± 1.0
|
|
Lactate (n = 18)
|
7.53 ± 0.03b,c
|
51 ± 7b,c
|
81 ± 26
|
41.4 ± 6.3b,c
|
16.8 ± 4.8b,c
|
2.3 ± 0.8c
|
|
48 hours
| | | | | | |
|
Control (n = 18)
|
7.42 ± 0.03
|
42 ± 9
|
87 ± 28
|
26.9 ± 5.6b
|
2.8 ± 5.3b
|
1.6 ± 0.9
|
|
Lactate (n = 18)
|
7.47 ± 0.03b
|
48 ± 4b
|
95 ± 42
|
34.2 ± 4.1b,c
|
9.6 ± 4.2b,c
|
1.2 ± 0.5b
|
- aBE = Base excess (mmol/L); HCO3- = Bicarbonate (mmol/L); PaCO2 = Partial pressure of carbon dioxide (mmHg); PaO2 = Partial pressure of oxygen (mmHg). bP < 0.01 compared to baseline values and cP < 0.01 for intergroup comparison. Data are expressed as mean ± SD.
