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Table 4 Multivariable linear regression for secondary outcomes*

From: Calorie intake and patient outcomes in severe acute kidney injury: findings from The Randomized Evaluation of Normal vs. Augmented Level of Replacement Therapy (RENAL) study trial

Variable name Estimate Standard error P-value
a. Multivariable linear regression for RRT-free days
Intercept −40.32510 33.71933 0.2323
Mean daily calorie intake during ICU admission 0.00189 0.00171 0.2695
Median daily calorie intake during ICU admission −1.09792 2.61145 0.6744
Positive mean fluid balance −4.09805 0.87492 <.0001
Treatment −1.97170 0.85163 0.0210
Time from ICU admission to randomization (in days) −0.01644 0.00469 0.0005
SOFA liver (score) −1.63540 0.44579 0.0003
APPT −0.05581 0.02105 0.0083
pH 8.45062 4.27094 0.0484
b. Multivariate linear regression of ICU-free days
Intercept −221.76773 281.51940 0.4313
Mean daily calorie intake during ICU admission 0.00468 0.00649 0.4714
Median daily calorie intake during ICU admission 2.89089 8.90361 0.7456
Positive mean fluid balance −19.69578 3.36383 <.0001
Positive ventilation: no = reference group −13.45268 5.58339 0.0165
Patient's weight (Kg) 0.45320 0.13896 0.0012
Time from ICU admission to randomization (days) −0.03736 0.01756 0.0340
Last creatinine concentration 0.11279 0.04434 0.0114
c. Multivariate linear regression of hospital-free days
Intercept 25.05875 258.60573 0.9229
Mean daily calorie intake during ICU admission −0.00349 0.00601 0.5625
Median daily calorie intake during ICU admission 2.11260 8.32222 0.7997
Positive mean fluid balance −16.17529 3.08521 <.0001
Patient's weight (Kg) 0.29499 0.12933 0.0231
Last serum urea concentration −3.72244 1.85441 0.0454
Last creatinine concentration 0.09767 0.04131 0.0185
Glucose (mmol/L) 1.09456 0.50830 0.0319
  1. *Only DCI related variable and significant variables reported. SOFA, sequential organ failure assessment; activated partial thromboplastin time.