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Table 4 Discriminatory accuracy of procalcitonin and C-reactive protein for detection of bacterial pneumonia a

From: Procalcitonin for diagnosis of bacterial pneumonia in critically ill patients during 2009 H1N1 influenza pandemic: a prospective cohort study, systematic review and individual patient data meta-analysis

Characteristics

AUC

95% CI

P-values

P-value vs. total population

Total (N = 161)

0.72

0.64 to 0.80

<0.0001

–

Without antibiotics before admission (n = 91)

0.73

0.62 to 0.83

<0.0001

0.47

Without ECMO or renal replacement therapy (n = 110)

0.74

0.64 to 0.83

<0.0001

0.40

Without hospital-acquired pneumonia (n = 131)

0.76

0.68 to 0.84

<0.0001

0.25

Without immune-compromising disorder (n = 140)

0.74

0.65 to 0.82

<0.0001

0.40

Without hospital-acquired pneumonia and

0.76

0.68 to 0.85

<0.0001

0.24

Without immune-compromising disorder (n = 124)

CRP (total population, n = 143)

0.64

0.55 to 0.73

0.003

0.10

  1. aAUC, Area under the curve; CI, 95% confidence interval; CRP, C-reactive protein; ECMO, extracorporeal membrane oxygenation.