- Meeting abstract
Effects of PEEP above the L-Pflexon gas exchange, hemodynamic and gastric tonometer in ARDSpatients
Critical Care volume 5, Article number: P43 (2001)
Introduction and method
In order to study the acute effects of optimal PEEP on oxygenation, CO2 exchange, hemodynamic parameters and gastric mucosal PCO2 we analyzed 10 ARDS patients (<5 days of installation) after 30 min on PEEP 5 cmH2O (T0), then 30 min on PEEP 2 cmH2O above the L-Pflex (T1) and than 30 min after PEEP of 5 cmH2O (T2). They were all sedated-paralyzed. A Swan-Ganz catheter with a semicontinuous cardiac output and continuous gastric tonometer was inserted in each patient. The tidal volume and respiratory rate were kept constant (8 ml/kg and 20/min; VCV). L-Pflex was titrated by PxV curve (random volumes). The mean APACHEII was 21.3.
Although cardiac index had decreased, PEEP titrated by L-Pflex of PxV curve of the respiratory system improved oxygenation without impairing regional hemodynamics in ARDS patients.
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Silva, E., Barbas, C., Garrido, A. et al. Effects of PEEP above the L-Pflexon gas exchange, hemodynamic and gastric tonometer in ARDSpatients. Crit Care 5 (Suppl 3), P43 (2001). https://doi.org/10.1186/cc1376
- Public Health
- Cardiac Output
- Respiratory Rate
- Emergency Medicine