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Table 2 Clinical characteristics of the patients in the validation study in survivors and non-survivors at 28 days

From: Circulating neutrophil counts and mortality in septic shock

  Total (n = 194) Survivors (n = 132) Non-survivors (n = 62) P
Patient details     
     Gender (male) 126 (64.9%) 85 (64.3%) 41 (66.1%) NS
     Age (years) 67.1 ± 13.3 65.3 ± 14.3 71.1 ± 9.5 <0.001
     Inmunosuppression 35 (18.0%) 15 (11.3%) 20 (32.2%) <0.001
     Diabetes 32 (16.4%) 21 (15.9%) 11 (17.7%) NS
     Cardiovascular disease 24 (12.3%) 14 (10.6%) 10 (16.1%) NS
     Cancer 18 (9.2%) 10 (7.5%) 8 (12.9%) NS
     COPD 23 (11.8%) 12 (9.0%) 11 (17.7%) NS
     Chronic renal failure 15 (7.7%) 10 (7.5%) 5 (8.0%) NS
     Alcohol abuse 12 (6.1%) 7 (5.3%) 5 (8.0%) NS
     Hepatic disease 4 (2.0%) 1 (0.7%) 3 (4.8%) NS
Clinical status at admission     
     APACHE II score 22.6 ± 7.0 21.0 ± 6.5 25.9 ± 7.1 <0.001
     Mechanical ventilation 150 (77.7%) 93 (70.9%) 57 (91.9%) <0.001
     OARF 39 (20.1%) 17 (12.8%) 22 (35.4%) <0.001
Presumed source of infection     
     Respiratory system 67 (34.5%) 45 (34.1%) 22 (35.5%) NS
     Digestive system 52 (26.8%) 32 (24.2%) 20 (32.3%) NS
     Urinary system 26 (13.4%) 21 (15.9%) 5 (8.1%) NS
     Catheter 16 (8.2%) 11 (8.3%) 5 (8.1%) NS
     Wound/skin, soft tissue 15 (7.7%) 11 (8.3%) 4 (6.5%) NS
     Other/unknown 18 (9.3%) 12 (9.1%) 6 (9.7%) NS
Documented microbial agent     
     Gram-negative 52 (26.8%) 36 (27.2%) 16 (25.8%) NS
     Gram-positive 33 (17.0%) 25 (18.9%) 8 (12.9%) NS
     Fungi 12 (6.1%) 4 (3.0%) 8 (12.9%) 0.020
Laboratory data     
     Bilirubin (mg/dL) 1.4 ± 2.2 1.4 ± 2.1 1.6 ± 2.4 NS
     Glycemia (mg/dL) 168 ± 64.0 167 ± 62.4 172.0 ± 67.6 NS
     INR 1.8 ± 3.1 1.9 ± 3.8 1.6 ± 0.6 NS
     Platelets (×103/μl) 177.4 ± 118.5 173.6 ± 105.2 186.4 ± 146.1 NS
     Leukocytes (×103/μl) 18.0 ± 16.4 18.4 ± 17.0 17.3 ± 15.3 NS
     Monocytes (×103/μl) 0.7 ± 1.7 0.8 ± 20.2 0.6 ± 0.9 NS
     Lymphocyte (×103/μl) 1.8 ± 70.5 1.6 ± 73.5 2.3 ± 64.1 NS
     Neutrophils (×103/μl) 14.9 ± 12.5 15.6 ± 12.9 13.6 ± 11.5 NS
     Basophils (×103/μl) 0.1 ± 0.0 0.1 ± 0.0 0.1 ± 0.0 NS
     Eosinophils (×103/μl) 0.1 ± 0.0 0.1 ± 0.0 0.1 ± 0.0 NS
  1. For the demographic characteristics of the patients, differences between groups were assessed using the χ2 test for categorical variables and the Student's t-test for continuous variables when appropriate. Continuous variables are expressed as mean ± standard deviation. APACHE, Acute Physiology and Chronic Health Evaluation; COPD, chronic obstructive pulmonary disease; INR, international normalized ratio; NS, not significant; OARF, oliguric acute renal failure.