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Figure 5 | Critical Care

Figure 5

From: Prothrombin complex concentrates and a specific antidote to dabigatran are effective ex-vivo in reversing the effects of dabigatran in an anticoagulation/liver trauma experimental model

Figure 5

Thromboelastometry parameters 60 minutes after trauma. Sixty minutes after stopping the dabigatran infusion and the infliction of blunt liver injury trauma, a ROTEM device was used to measure the impact of dabigatran reversal. Data are shown as the mean ± SD. *P <0.05 versus control. PCC, prothrombin complex concentrate; aPCC, activated PCC; rFVIIa, recombinant activated factor VII; aDabi-Fab, antibody fragment to dabigatran.

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