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Table 3 Treatment indication, modality, and anticoagulation of renal replacement therapy (RRT) in the low-RRT and high-RRT intensive care units (ICUs)

From: Variation in the use of renal replacement therapy in patients with septic shock: a substudy of the prospective multicenter observational FINNAKI study

 

Low-RRT ICUs (n = 33)

High-RRT ICUs (n = 98)

P value

Indication of RRT

   

Oliguria

29 (87.9)

83 (84.7)

0.7

High creatinine

25 (75.8)

54 (55.1)

0.04

Acidosis

24 (72.7)

72 (73.5)

0.9

Hyperkalemia

9 (27.3)

20 (20.4)

0.4

Fluid overload

12 (36.4)

43 (43.9)

0.4

Intoxication

2 (6.1)

3 (3.0)

0.4

Modality of RRT

   

  Only CRRT during ICU

20 (60.6)

52 (53.1)

0.5

  Only IRRT during ICU

2 (6.1)

11 (11.2)

0.4

  Both CRRT + IRRT during ICU

11 (33.3)

35 (35.7)

0.8

Time to initiation of RRT from ICU admission (hours)

17.8 [5.2–33.7]

13.5 [5.2–33.2]

0.9

Received anticoagulation

32 (97)

83 (84.7)

0.06

  Citrate

23 (69.7)

40 (40.8)

0.004

  LMWH

18 (54.5)

65 (66.3)

0.2

  Other

0

7 (7.1)

0.1

  None

4 (12.1)

27 (27.6)

0.07

Complications related to RRT

  Complication in insertion of catheter

8 (24.2)

10 (10.2)

0.04

  Electrolyte disturbances

7 (21.2)

19 (19.4)

0.8

  Hypotension during RRT

1 (3.0)

2 (2.0)

0.7

  Bleeding

2 (6.1)

1 (1.0)

0.09

  Catheter-related infection

0

1 (1.0)

0.6

  1. Values are expressed as count (%) and median [interquartile range]. CRRT, continuous renal replacement therapy; IRRT, intermittent renal replacement therapy; LMWH, low-molecular-weight heparin.