Table 1 Demographic of patients with septic shock divided by low- or high-renal replacement therapy (RRT) intensive care units (ICUs)
Patients in low-RRT ICUs (n = 372) | Patients in high-RRT ICUs (n = 354) | P value | |
|---|---|---|---|
Age (years) | 64.0 [54.0–74.0] | 67.0 [56.0–76.0] | 0.04 |
Gender (male) | 243 (65.3) | 221 (62.4) | 0.4 |
Any comorbidity1 | 237 (64.9) | 250 (71.2) | 0.07 |
Community-acquired infection | 103 (29.5) | 106 (32.8) | 0.4 |
Source of infection | |||
Pulmonary | 186 (54.4) | 165 (52.1) | 0.5 |
Abdominal | 84 (24.6) | 108 (34.1) | 0.007 |
Genitourinary | 21 (6.1) | 26 (8.2) | 0.3 |
Soft tissue | 47 (13.7) | 24 (7.6) | 0.01 |
Emergency admission | 370 (99.5) | 334 (94.4) | <0.001 |
Operative admission | 89 (23.9) | 114 (32.2) | 0.01 |
SAPS without age and renal components | 27.0 [21.0–36.0] | 26.0 [19.0–34.0] | 0.02 |
SOFA D1 | 9.0 [7.0–11.0] | 9.0 [7.0–11.0] | 0.08 |
APACHE II diagnostic group | |||
Respiratory tract, nonoperative | 92 (24.7) | 82 (23.2) | 0.6 |
Nonoperative sepsis | 72 (19.4) | 64 (18.1) | 0.7 |
Gastrointestinal tract, operative | 56 (15.1) | 71 (20.1) | 0.08 |
Gastrointestinal tract, nonoperative | 32 (8.6) | 30 (8.5) | 0.9 |
Cardiovascular, nonoperative | 30 (8.1) | 31 (8.8) | 0.7 |
Neurological, nonoperative | 16 (4.3) | 7 (2.0) | 0.07 |
Metabolic | 16 (4.3) | 7 (2.0) | 0.07 |
Trauma | 12 (3.2) | 5 (1.4) | 0.1 |
Neurological, operative | 11 (3.0) | 2 (0.6) | 0.02 |
Cardiovascular, operative | 5 (1.3) | 21 (5.9) | 0.001 |
Treatment restrictions | |||
Any treatment restriction2 | 100 (26.9) | 104 (29.4) | 0.5 |
Withholding of RRT | 28 (7.5) | 16 (4.5) | 0.09 |
Outcomes | |||
Length of stay ICU (days) | 4.1 [2.1–8.1] | 4.7 [2.7–8.3] | 0.09 |
Length of stay hospital (days) | 15.0 [8.0–25.0] | 14.0 [7.0–24.0] | 0.2 |
90-day mortality | 126 (33.9) | 128 (36.2) | 0.5 |
Probability of death3 | 0.33 [0.17–0.62] | 0.37 [0.17–0.64] | 0.4 |
SMR (95% CI) | 0.72 (0.6–0.84) | 0.66 (0.58–0.74) | |
Propensity for RRT4 | 0.06 [0.03–0.15] | 0.06 [0.03–0.24] | 0.01 |