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Figure 1 | Critical Care

Figure 1

From: Combination of thrombin-antithrombin complex, plasminogen activator inhibitor-1, and protein C activity for early identification of severe coagulopathy in initial phase of sepsis: a prospective observational study

Figure 1

Time course of overt DIC scores and hemostatic biomarkers from baseline to Day 3. Overt disseminated intravascular coagulation (DIC) scores, platelet count, prothrombin time-international normalized ratio (PT-INR), fibrin degradation product (FDP), thrombin-antithrombin complex (TAT), plasminogen activator inhibitor-1 (PAI-1) and protein C (PC) for patients with and without subsequent development of overt DIC (gray vs. white bars), and for survivors (dotted line) and non-survivors (solid line) among patients with overt DIC. Data are expressed as mean and 95% CI. *P <0.05 between patients with and without overt DIC on the same day. **P <0.05 between patients on Day 0 versus Day 2. +P <0.05 between survivors and non-survivors with overt DIC on the same day.

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