Skip to main content

Table 2 Influx of neutrophils in bronchiolar lavage fluid of wild-type, tlr4−/−or Rage−/−mice

From: High-mobility group box 1 and the receptor for advanced glycation end products contribute to lung injury during Staphylococcus aureus pneumonia

Time point (t)

Wild-type

Tlr4 −/−

Rage −/−

t = 6 h

239 (217 to 310)

397 (221 to 535)

526 (350 to 647)

t = 24 h

298 (250 to 380)

236 (196 to 275)

342 (262 to 404)

t = 48 h

429 (218 to 652)

522 (421 to 756)

395 (314 to 541)

t = 72 h

146 (99 to 190)

90 (81 to 132)

76 (47 to 104)*

  1. Neutrophil numbers (×1000/ml) in bronchiolar lavage fluid at 6, 24, 48 and 72 hours after intranasal S. aureus infection in wild-type (Wt), Toll-like receptor (tlr)4−/− and Receptor for advanced glycation end products (Rage)−/− mice. Data are medians (interquartile ranges); n = 7 to 8 mice per group per time point. *P <0.05 versus Wt mice at the same time point.