Figure 1From: High-mobility group box 1 and the receptor for advanced glycation end products contribute to lung injury during Staphylococcus aureus pneumoniaHigh mobility group box 1 (HMGB1) concentrations in mouse bronchoalveolar lavage (BAL) fluid during S. aureus pneumonia. Wt mice were intranasally infected with 1 × 107 colony forming units (CFU) S. aureus and euthanized after 6, 24, 48 and 72 hours. HMGB1 concentrations in BAL fluid were quantified by densometric analysis of HMGB1 western blots and expressed as a percentage of the mean density of control BAL fluid samples (0 hours). Data represent the means ± standard error of the mean (n = 5 mice per time point). *P <0.05 versus naïve mice (0 hours).Back to article page