Skip to main content

Table 3 Histopathologic scoring for severity of acute porcine pancreatitis

From: Effects of thoracic epidural anesthesia on survival and microcirculation in severe acute pancreatitis: a randomized experimental trial

Histopathologic severity score of acute pancreatis

Group

Acinar necrosis*

Fatty tissue necrosis*

Inflammation

Edema*

Overall*

Group 1 (TEA)

2 (0–3)

1 (0–2)

2 (0–2)

1 (0–2)

5.5 (3–8)

Group 2 (CONTROL)

3 (0–3)

2 (1–3)

2 (1–3)

1.5 (0.5-3)

8 (5.5-10)

 

Acinar necrosis

Fatty tissue necrosis (in relation to plane)

Inflammation (plasma cells, lymphocytes and granulocytes outside parechymal and fatty tissue)

Edema

 
 

0 nil

0 nil

0 nil

0 nil

 
 

1 <10 single necrosis/lobule

1 <1/3 of plane

1 loose infiltrates (≤30 cells/HPF)

1 intralobular edema

 
 

2 ≥10 single necrosis/lobule

2 ≥1/3 to <2/3 of plane

2 moderate infiltrates (30–99 cells/HPF)

2 interacinar edema, ≥2 lobules

 

* P < 0.05

3 ≥1/3 of plane

3 ≥2/3 of plane

3 dense infiltrates (≥100 cells/HPF)

3 intercellular edema, ≥2 lobules

 
  1. *P <0.05 representing statistically significant difference. Data are presented as median (range); Pancreatitis Score: 0 (no pancreatitis) to 12 (severe pancreatitis); histopathologic pancreatitis score (0 to 12 points) including acinar necrosis (0 to 3) fatty tissue necrosis (0 to 3), inflammation (0 to 3) and Edema (0 to 3). HPF: High power field; TEA, thoracic epidural anesthesia.