Table 1 Patient characteristics
Characteristics and outcomes | Overall | Derivation cohort | Validation cohort | P value |
|---|---|---|---|---|
|  | (number = 3,255) | (number = 1,953) | (number = 1,302) |  |
Demographics | Â | Â | Â | Â |
 Age, years, median (IQR) | 62 (53–72) | 62 (53–72) | 62 (52–72) | 0.12 |
 Gender (male), n (%) | 1995 (61.3) | 1189 (80.9) | 806 (61.9) | 0.56 |
Risk factors, n (%) | Â | Â | Â | Â |
 Hypertension | 2210 (67.9) | 1338 (68.5) | 872 (67.0) | 0.36 |
 Diabetes mellitus | 290 (8.9) | 179 (9.2) | 111 (8.5) | 0.53 |
 Dyslipidemia | 230 (7.1) | 148 (7.6) | 82 (6.3) | 0.16 |
 Atrial fibrillation | 54 (1.7) | 33 (1.7) | 21 (1.6) | 0.87 |
 Coronary heart disease | 204 (6.3) | 123 (6.3) | 81 (6.2) | 0.93 |
 History of stroke/TIA | 889 (27.3) | 543 (27.8) | 346 (26.6) | 0.44 |
 Current smoker | 1228 (37.7) | 734 (37.6) | 494 (37.9) | 0.83 |
 Heavy alcohol consumption | 367 (11.3) | 223 (11.4) | 144 (11.1) | 0.75 |
Transport to hospital by EMS, n (%) | 1029 (31.6) | 625 (32.0) | 404 (31.0) | 0.75 |
Pre-admission anticoagulation, n (%) | 32 (1.0) | 20 (1.0) | 12 (0.9) | 0.86 |
Pre-admission antiplatelet, n (%) | 291 (8.9) | 173 (8.9) | 118 (9.1) | 0.85 |
Pre-admission statin, n (%) | 228 (7.0) | 146 (7.5) | 82 (6.3) | 0.21 |
Admission NIHSS score, median (IQR) | 9 (3–16) | 9 (3–16) | 9 (3–17) | 0.98 |
Admission GCS score, median (IQR) | 14 (9–15) | 14 (9–15) | 14 (9–15) | 0.51 |
Admission SBP (mm Hg), median (IQR) | 160 (147–180) | 160 (147–180) | 160 (146–180) | 0.17 |
Admission DBP (mm Hg), median (IQR) | 95 (87–106) | 94 (87–105) | 96 (87–108) | 0.13 |
Admission WBC, 109/L, median (IQR) | 8.7 (6.7-11.3) | 8.6 (6.7-11.2) | 8.8 (6.7-11.6) | 0.37 |
Admission hemoglobin, g/dL, median (IQR) | 139 (126–150) | 139 (126–150) | 139 (127–150) | 0.72 |
Admission platelet, 109/L, median (IQR) | 186 (145–230) | 187 (143–232) | 185 (147–227) | 0.83 |
Admission glucose (mmol/L), median (IQR) | 6.3 (5.7-7.5) | 6.3 (5.7-7.5) | 6.3 (5.7-7.5) | 0.58 |
Admission creatinine (mmol/L), median (IQR) | 77.0 (62.0-92.0) | 77 (62–92) | 76 (61–92) | 0.39 |
Infratentorial ICH, n (%) | 393 (12.1) | 229 (11.7) | 164 (12.6) | 0.46 |
Hematoma volume (cm3), median (IQR) | 12.6 (5.5-28.0) | 12.8 (5.2-28.1) | 12.3 (5.7-28.0) | 0.93 |
Intraventricular extension, n (%) | 962 (29.6) | 587 (30.1) | 375 (28.8) | 0.44 |
Withdrawal of medical care, n (%) | 404 (12.4) | 247 (12.6) | 157 (12.1) | 0.63 |
Academic hospital, n (%) | 1724 (53.0) | 1043 (53.4) | 681 (52.3) | 0.55 |
Surgical treatment | 81 (2.5) | 50 (2.6) | 31 (2.4) | 0.82 |
mRS score at one year after ICH, n (%) | Â | Â | Â | 0.73 |
mRS = 0 | 691 (21.2) | 409 (20.9) | 282 (21.7) |  |
 mRS = 1 | 743 (22.8) | 442 (22.6) | 301 (23.1) |  |
 mRS = 2 | 324 (10.0) | 190 (9.7) | 134 (10.3) |  |
 mRS = 3 | 318 (9.8) | 196 (10.0) | 122 (9.4) |  |
 mRS = 4 | 238 (7.3) | 134 (6.9) | 104 (8.0) |  |
 mRS = 5 | 92 (2.8) | 56 (2.9) | 36 (2.8) |  |
 mRS = 6 | 849 (26.1) | 526 (26.9) | 323 (24.8) |  |