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Table 1 Patient characteristics

From: A novel risk score to predict 1-year functional outcome after intracerebral hemorrhage and comparison with existing scores

Characteristics and outcomes Overall Derivation cohort Validation cohort P value
  (number = 3,255) (number = 1,953) (number = 1,302)  
Demographics     
 Age, years, median (IQR) 62 (53–72) 62 (53–72) 62 (52–72) 0.12
 Gender (male), n (%) 1995 (61.3) 1189 (80.9) 806 (61.9) 0.56
Risk factors, n (%)     
 Hypertension 2210 (67.9) 1338 (68.5) 872 (67.0) 0.36
 Diabetes mellitus 290 (8.9) 179 (9.2) 111 (8.5) 0.53
 Dyslipidemia 230 (7.1) 148 (7.6) 82 (6.3) 0.16
 Atrial fibrillation 54 (1.7) 33 (1.7) 21 (1.6) 0.87
 Coronary heart disease 204 (6.3) 123 (6.3) 81 (6.2) 0.93
 History of stroke/TIA 889 (27.3) 543 (27.8) 346 (26.6) 0.44
 Current smoker 1228 (37.7) 734 (37.6) 494 (37.9) 0.83
 Heavy alcohol consumption 367 (11.3) 223 (11.4) 144 (11.1) 0.75
Transport to hospital by EMS, n (%) 1029 (31.6) 625 (32.0) 404 (31.0) 0.75
Pre-admission anticoagulation, n (%) 32 (1.0) 20 (1.0) 12 (0.9) 0.86
Pre-admission antiplatelet, n (%) 291 (8.9) 173 (8.9) 118 (9.1) 0.85
Pre-admission statin, n (%) 228 (7.0) 146 (7.5) 82 (6.3) 0.21
Admission NIHSS score, median (IQR) 9 (3–16) 9 (3–16) 9 (3–17) 0.98
Admission GCS score, median (IQR) 14 (9–15) 14 (9–15) 14 (9–15) 0.51
Admission SBP (mm Hg), median (IQR) 160 (147–180) 160 (147–180) 160 (146–180) 0.17
Admission DBP (mm Hg), median (IQR) 95 (87–106) 94 (87–105) 96 (87–108) 0.13
Admission WBC, 109/L, median (IQR) 8.7 (6.7-11.3) 8.6 (6.7-11.2) 8.8 (6.7-11.6) 0.37
Admission hemoglobin, g/dL, median (IQR) 139 (126–150) 139 (126–150) 139 (127–150) 0.72
Admission platelet, 109/L, median (IQR) 186 (145–230) 187 (143–232) 185 (147–227) 0.83
Admission glucose (mmol/L), median (IQR) 6.3 (5.7-7.5) 6.3 (5.7-7.5) 6.3 (5.7-7.5) 0.58
Admission creatinine (mmol/L), median (IQR) 77.0 (62.0-92.0) 77 (62–92) 76 (61–92) 0.39
Infratentorial ICH, n (%) 393 (12.1) 229 (11.7) 164 (12.6) 0.46
Hematoma volume (cm3), median (IQR) 12.6 (5.5-28.0) 12.8 (5.2-28.1) 12.3 (5.7-28.0) 0.93
Intraventricular extension, n (%) 962 (29.6) 587 (30.1) 375 (28.8) 0.44
Withdrawal of medical care, n (%) 404 (12.4) 247 (12.6) 157 (12.1) 0.63
Academic hospital, n (%) 1724 (53.0) 1043 (53.4) 681 (52.3) 0.55
Surgical treatment 81 (2.5) 50 (2.6) 31 (2.4) 0.82
mRS score at one year after ICH, n (%)     0.73
mRS = 0 691 (21.2) 409 (20.9) 282 (21.7)  
 mRS = 1 743 (22.8) 442 (22.6) 301 (23.1)  
 mRS = 2 324 (10.0) 190 (9.7) 134 (10.3)  
 mRS = 3 318 (9.8) 196 (10.0) 122 (9.4)  
 mRS = 4 238 (7.3) 134 (6.9) 104 (8.0)  
 mRS = 5 92 (2.8) 56 (2.9) 36 (2.8)  
 mRS = 6 849 (26.1) 526 (26.9) 323 (24.8)  
  1. DBP, diastolic blood pressure; EMS, Emergency Medical System; GCS, Glasgow Coma Scale; ICH, intracerebral hemorrhage; IQR, interquartile range; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale score; SBP, systolic blood pressure; TIA, transient ischemic attack; WBC, white blood cell count.