Table 1 Baseline characteristics

Patients

14

14

Age (years)

64 ± 8 (50 to 80)

67 ± 13 (35 to 80)

0.48

Gender (male/female)

11/3

9/5

0.68

Septic focus

0.36

 Abdomen

7

8

 Lung

6

3

 Other

1

3

Level of sepsis

0.34

 Sepsis

0

2

 Severe sepsis

1

1

 Septic shock

13

11

APACHE II score

34.9 ± 8.4 (18 to 49)

19.1 ± 6.4 (10 to 27)

<0.001

SAPS II score

59.1 ± 19.6 (23 to 90)

44.4 ± 16.1 (18 to 68)

0.043

SOFA score

11.4 ± 4.8 (23 to 90)

6.9 ± 3.8 (0 to 13)

0.017

Procalcitonin (ng/ml)

25.6 ± 25.6 (1.1 to 73)

20.4 ± 27.3 (0.9 to 75)

0.60

C-reactive protein (mg/l)

184 ± 72 (91 to 330)

139 ± 91 (40 to 290)

0.17

Temperature (°C)

37.2 ± 1.4 (35.0 to 39.5)

37.9 ± 0.9 (36.5 to 39.8)

0.14

WBC (/nl)

20.6 ± 16.9 (1.1 to 46.6)

10.4 ± 7.8 (1.4 to 27.3)

0.051

Heart rate (/minute)

112 ± 22 (80 to 160)

112 ± 26 (75 to 170)

0.91

MAP (mmHg)

69.8 ± 7.6 (55 to 80)

69.4 ± 7.5 (55 to 85)

0.89

Noradrenalin (μg/kg/minute)

0.42 ± 0.44 (0 to 1.50)

0.12 ± 0.09 (0 to 0.26)

0.024

Dobutamine (μg/kg/minute)

1.3 ± 2.6 (0 to 8.7)

0.3 ± 1.0 (0 to 3.8)

0.19

Lactate (mmol/l)

6.2 ± 5.5 (0.6 to 16.6)

2.4 ± 1.8 (1 to 8.2)

0.028

pH

7.25 ± 0.10 (7.05 to 7.41)

7.33 ± 0.10 (7.03 to 7.45)

0.031

Bilirubin (μmol/l)

22 ± 18 (5 to 63)

11 ± 13 (3 to 53)

0.084

INR

1.7 ± 0.32 (1.39 to 2.44)

1.35 ± 0.19 (1.13 to 1.69)

0.002

LiMAx (μg/kg/hour)

127 ± 88 (43 to 384)

289 ± 117 (101 to 469)

<0.001

ICG-PDR (%/minute)

8.8 ± 4.0 (3.4 to 16.9)

25.0 ± 8.2 (14.3 to 39.6)

<0.001