Table 1 Hemodynamic parameters at different time points
Control | Epinephrine | Levosimendan | ||
|---|---|---|---|---|
HR bpm | T0 | 360 ± 16 | 354 ± 13 | 342 ± 12 |
T1 | 340 ± 9 | 346 ± 7 | 322 ± 9 | |
T2 | 352 ± 11 | 362 ± 11 | 355 ± 10 | |
MAP mmHg | T0 | 130 ± 11 | 127 ± 12 | 129 ± 13 |
T1 | 92 ± 9 | 85 ± 8 | 87 ± 8 | |
T2 | 85 ± 6* | 164 ± 13* | 112 ± 10 | |
LVESP mmHg | T0 | 95.2 ± 4.3 | 92.2 ± 6.4 | 93.4 ± 5.7 |
T1 | 66.2 ± 7.4 | 58.4 ± 5.1 | 63.5 ± 6.0 | |
T2 | 72.4 ± 8.9* | 104.3 ± 9.2 | 98.5 ± 4.7 | |
LVEDP mmHg | T0 | 8.2 ± 0.8 | 8.0 ± 0.5 | 8.6 ± 0.6 |
T1 | 12.2 ± 1.4 | 11.8 ± 2.1 | 12.5 ± 1.8 | |
T2 | 13.4 ± 0.9* | 11.6 ± 0.8* | 8.1 ± 0.5 | |
SV μL | T0 | 65 ± 10 | 63 ± 9 | 63 ± 6 |
T1 | 23 ± 8 | 25 ± 9 | 23 ± 9 | |
T2 | 25 ± 10* | 41 ± 9* | 58 ± 7 | |
CO ml/min | T0 | 43 ± 3 | 47 ± 5 | 45 ± 5 |
T1 | 15 ± 6 | 13 ± 8 | 14 ± 5 | |
T2 | 16 ± 10* | 21 ± 5* | 38 ± 7 | |
CI ml/min/100 g BW | T0 | 9.02 ± 1.92 | 9.02 ± 1.92 | 10.8 ± 1.22 |
T1 | 4.01 ± 0.51 | 4.21 ± 0.48 | 4.21 ± 0.48 | |
T2 | 4.35 ± 0.60* | 4.95 ± 0.73* | 9.95 ± 1.43 | |
dP/dt max mmHg/s | T0 | 7,305 ± 184 | 7,427 ± 193 | 7,289 ± 201 |
T1 | 4,667 ± 145 | 4,588 ± 210 | 4,644 ± 185 | |
T2 | 4,850 ± 174* | 7,171 ± 189 | 7,221 ± 174 | |
dP/dt min mmHg/s | T0 | 7,672 ± 306 | 7,511 ± 285 | 7,622 ± 297 |
T1 | 4,856 ± 288 | 4,992 ± 199 | 4,741 ± 283 | |
T2 | 4,510 ± 190* | 5,701 ± 189* | 7,485 ± 190 | |
TPRI mmHg/ml/min/100 g BW | T0 | 2.78 ± 0.22 | 2.63 ± 0.18 | 2.57 ± 0.25 |
T1 | 1.98 ± 0.19 | 1.88 ± 0.21 | 1.90 ± 0.23 | |
T2 | 2.12 ± 0.25* | 5.70 ± 0.70* | 2.60 ± 0.31 |