From: Risk of developing severe sepsis after acute kidney injury: a population-based cohort study
Patient characteristics | Non-AKI group | AKI group | P-value |
---|---|---|---|
(N = 11,932) | (N = 2,983) | ||
Mean age (years) | 62.03 ± 14.84 | 62.03 ± 14.84 | 0.995 |
Males (%) | 6,004 (50.3%) | 1,501 (50.3%) | 0.999 |
Admission frequency | 0.57 ± 1.61 | 2.28 ± 2.75 | <0.001 |
Charlson Comorbidity Index score | 1.67 ± 1.72 | 3.66 ± 2.17 | <0.001 |
Comorbidities (before admission) | |||
 Myocardial infarction | 122 (1%) | 89 (3%) | <0.001 |
 Congestive heart failure | 426 (3.6%) | 549 (18.4%) | <0.001 |
 Peripheral vascular disease | 161 (1.3%) | 102 (3.4%) | <0.001 |
 Cerebrovascular disease | 1,117 (9.4%) | 477 (16%) | <0.001 |
 Dementia | 204 (1.7%) | 87 (2.9%) | <0.001 |
 COPD | 1,854 (15.5%) | 497 (16.7%) | 0.137 |
 Rheumatologic disease | 158 (1.3%) | 55 (1.8%) | 0.038 |
 Peptic ulcer | 2,182 (18.3%) | 786 (26.3%) | <0.001 |
 Moderate or severe liver disease | 1,288 (10.8%) | 285 (9.6%) | 0.049 |
 Diabetes mellitus | 5,973 (50.1%) | 1,494 (50.1%) | 0.984 |
 Hemiplegia | 147 (1.2%) | 68 (2.3%) | <0.001 |
 Chronic kidney disease | 845 (7.1%) | 2,248 (75.4%) | <0.001 |
 Solid tumor | 657 (5.5%) | 193 (6.5%) | 0.047 |
 Tumor with metastasis | 198 (1.7%) | 40 (1.3%) | 0.252 |
Comorbidities (during index hospitalization) | |||
 Cardiovascular | 89 (0.7%) | 84 (2.8%) | <0.001 |
 Respiratory | 100 (0.8%) | 286 (9.6%) | <0.001 |
 Hepatic | 96 (0.8%) | 36 (1.2%) | 0.048 |
 Neurologic | 18 (0.2%) | 48 (1.6%) | <0.001 |
 Hematologic | 56 (0.5%) | 29 (1%) | 0.002 |
 Metabolic | 5 (0%) | 98 (3.3%) | <0.001 |
Operative categories | |||
 Cardiothoracic | 78 (0.7%) | 51 (1.7%) | <0.001 |
 Upper GI | 72 (0.6%) | 12 (0.4%) | 0.219 |
 Lower GI | 128 (1.1%) | 20 (0.7%) | 0.049 |
 Hepatobiliary | 197 (1.7%) | 13 (0.4%) | <0.001 |
ICU admission during index hospitalization | 898 (7.5%) | 948 (31.8%) | <0.001 |
Mechanical ventilation | 376 (3.2%) | 527 (17.7%) | <0.001 |
Mortality | 2603 (21.8%) | 1,386 (46.5%) | <0.001 |
Severe sepsis | 1,250 (10.5%) | 675 (22.6%) | <0.001 |