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Table 2 Baseline characteristics of study population stratified by acute kidney injury a

From: Risk of developing severe sepsis after acute kidney injury: a population-based cohort study

Patient characteristics Non-AKI group AKI group P-value
(N = 11,932) (N = 2,983)
Mean age (years) 62.03 ± 14.84 62.03 ± 14.84 0.995
Males (%) 6,004 (50.3%) 1,501 (50.3%) 0.999
Admission frequency 0.57 ± 1.61 2.28 ± 2.75 <0.001
Charlson Comorbidity Index score 1.67 ± 1.72 3.66 ± 2.17 <0.001
Comorbidities (before admission)
 Myocardial infarction 122 (1%) 89 (3%) <0.001
 Congestive heart failure 426 (3.6%) 549 (18.4%) <0.001
 Peripheral vascular disease 161 (1.3%) 102 (3.4%) <0.001
 Cerebrovascular disease 1,117 (9.4%) 477 (16%) <0.001
 Dementia 204 (1.7%) 87 (2.9%) <0.001
 COPD 1,854 (15.5%) 497 (16.7%) 0.137
 Rheumatologic disease 158 (1.3%) 55 (1.8%) 0.038
 Peptic ulcer 2,182 (18.3%) 786 (26.3%) <0.001
 Moderate or severe liver disease 1,288 (10.8%) 285 (9.6%) 0.049
 Diabetes mellitus 5,973 (50.1%) 1,494 (50.1%) 0.984
 Hemiplegia 147 (1.2%) 68 (2.3%) <0.001
 Chronic kidney disease 845 (7.1%) 2,248 (75.4%) <0.001
 Solid tumor 657 (5.5%) 193 (6.5%) 0.047
 Tumor with metastasis 198 (1.7%) 40 (1.3%) 0.252
Comorbidities (during index hospitalization)
 Cardiovascular 89 (0.7%) 84 (2.8%) <0.001
 Respiratory 100 (0.8%) 286 (9.6%) <0.001
 Hepatic 96 (0.8%) 36 (1.2%) 0.048
 Neurologic 18 (0.2%) 48 (1.6%) <0.001
 Hematologic 56 (0.5%) 29 (1%) 0.002
 Metabolic 5 (0%) 98 (3.3%) <0.001
Operative categories
 Cardiothoracic 78 (0.7%) 51 (1.7%) <0.001
 Upper GI 72 (0.6%) 12 (0.4%) 0.219
 Lower GI 128 (1.1%) 20 (0.7%) 0.049
 Hepatobiliary 197 (1.7%) 13 (0.4%) <0.001
ICU admission during index hospitalization 898 (7.5%) 948 (31.8%) <0.001
Mechanical ventilation 376 (3.2%) 527 (17.7%) <0.001
Mortality 2603 (21.8%) 1,386 (46.5%) <0.001
Severe sepsis 1,250 (10.5%) 675 (22.6%) <0.001
  1. aAKI: acute kidney injury; COPD: chronic obstructive pulmonary disease; GI: gastrointestinal.