Figure 2

Septic and normal/N-formyl- l -methionyl- l -leucyl- l -phenylalanine neutrophils induce similar patterns of barrier dysfunction. Change in monolayer resistance at 30 minutes, 60 minutes, and 180 minutes. Groups were analyzed using two-way analysis of variance with Holm–Sidak post-hoc analysis. Values presented as mean ± standard error of the mean. Both normal/N-formyl-l-methionyl-l-leucyl-l-phenylalanine (fMLP) and septic patient neutrophils caused a greater change in barrier function than untreated normal neutrophils; however, there was no difference between normal/fMLP and septic patient neutrophils at any time point. *P <0.05 vs. normal.