Incidence, risk factors and prediction of post-operative acute kidney injury following cardiac surgery for active infective endocarditis: an observational study

Table 3 Factors associated with impairment in renal function after surgery

	RR	95% CI	P-value	OR	95% CI	P-value
Multiple surgery	1.83	1.54, 2.18	<0.001	4.16	2.98, 5.80	<0.001
Vancomycin administration	1.57	1.37, 1.81	<0.001	2.63	2.07, 3.34	<0.001
Aminoglycoside administration	1.23	1.07, 1.41	0.004	1.44	1.13, 1.83	0.004
Vancomycin:aminoglycoside interaction	1.54	1.34, 1.76	<0.001	2.62	2.08, 3.31	<0.001
Contrast agent	1.33	1.18, 1.51	<0.001	1.70	1.37, 2.12	<0.001
Transfusion	1.62	1.27, 2.07	<0.001	2.38	1.55, 3.63	<0.001
Pre-operative hemoglobin (<10 g/dl)	1.39	1.15, 1.67	0.001	1.89	1.34, 2.66	<0.001
Age (>65 y)	0.57	0.47, 0.70	<0.001	0.41	0.30, 0.57	<0.001

The variable importance measure for the risk factors associated with post-operative renal function impairment was performed after adjusting for all other covariates. RR, relative risk, OR, odds ratio.

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