Table 2 Technical features of the rapid PCR test
All patients | Se (%) [95% CI] | Sp (%) [95% CI] | PPV (%) [95% CI] | NPV (%) [95% CI] | LR + | LR - | Youden index |
|---|---|---|---|---|---|---|---|
MSSA (Rapid PCR) | 95.8 [78.9 to 99.9] | 83.2 [78.9 to 86.9] | 27.7 [18.4 to 38.6] | 99.7 [98.1 to 99.9] | 5.7 | 0.05 | 0.79 |
MSSA* (Rapid PCR) | 96.3 [81.0 to 99.9] | 75.2 [70.6 to 79.4] | 21.0 [14.2 to 29.2] | 99.7 [98.1 to 99.9] | 3.9 | 0.05 | 0.72 |
MSSA (Rapid PCR) | 85.2 [66.3 to 95.8] | 84.8 [80.9 to 88.2] | 27.1 [18.5 to 38.6] | 98.8 [97.0 to 99.7] | 5.6 | 0.18 | 0.70 |
MSSA (Gram stain) | 62.9 [42.4 to 80.6] | 80.7 [76.5 to 84.5] | 18.3 [11.0 to 27.7] | 97.0 [94.5 to 98.5] | 3.3 | 0.5 | 0.44 |
MRSA (Rapid PCR) | 80.0 [28.4 to 99.5] | 99.5 [98.3 to 99.9] | 66.7 [22.3 to 95.7] | 99.8 [98.7 to 99.9] | 166.8 | 0.2 | 0.79 |
MRSA* (Rapid PCR) | 100.0 [47.8 to 100.0] | 71.5 [66.9 to 75.8] | 4.0 [1.3 to 9.2] | 100.0 [98.7 to 100.0] | 3.5 | 0.00 | 0.72 |
MRSA (Rapid PCR) | 100.0 [47.8 to 100.0] | 80.3 [77.2 to 84.9] | 6.0 [2.0 to 13.5] | 100.0 [98.9 to 100.0] | 5.3 | 0.00 | 0.81 |
MRSA (Gram stain) | 40.0 [5.3 to 85.3] | 78.2 [73.9 to 82.1] | 2.2 [0.3 to 7.6] | 99.1 [97.4 to 99.8] | 1.8 | 0.8 | 0.18 |
≥ One risk factor | Se (%) | Sp (%) | PPV (%) | NPV (%) | LR + | LR - | Youden index |
MRSA | 80 [28.4 to 99.5] | 99.3 [97.6 to 99.9] | 66.7 [22.3 to 95.7] | 99.7 [98.1 to 99.9] | 118.4 | 0.2 | 0.79 |