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Table 2 Microdialysis parameters for myocardium and skeletal muscle

From: Depletion of myocardial glucose is observed during endotoxemic but not hemorrhagic shock in a porcine model

 

Myocardium

Skeletal muscle

 
 

Mean difference(CI)

P (mean)

Max difference(CI)

P (max)

Mean difference (CI)

P (mean)

Max difference (CI)

P (max)

Glucose

Glucose

C vs H

-0.4(-1.1 to 0.3)

0.282

-1.2(-2.6 to 0.3)

0.109

-0.4(-1.0 to 0.2)

0.155

-0.8(-1.5 to 0)

0.060

C vs E

-1.5(-2.2 to -0.8)

<0.001

-2.5(-4.0 to -0.9)

0.003

-0.8(-1.4 to -0.3)

0.007

-1.4(-2.2 to -0.6)

0.002

H vs E

-1.1(-1.8 to -0.4)

0.004

-1.4(-2.8 to 0.0)

0.043

-0.4(-1.0 to 0.1)

0.111

-1.0(-1.7 to -0.2)

0.016

Lactate

Lactate

C vs H

2.5(0.5 to 4.4)

0.016

3.4(1.1 to 5.7)

0.006

2.0(0.1 to 3.9)

0.041

2.8(0.5 to 5.0)

0.018

C vs E

2.2(0.2 to 4.1)

0.032

2.7(0.4 to 4.9)

0.013

1.7(-0.2 to 3.7)

0.083

2.9(0.5 to 5.3)

0.020

H vs E

-0.3(-2.2 to 1.6)

0.740

-1.7(-3.8 to 0.5)

0.118

-0.3(-2.2 to 1.6)

0.743

1.3(-1.0 to 3.6)

0.243

Pyruvate

Pyruvate

C vs H

120(65 to 176)

<0.001

148(65 to 232)

0.001

43(-30 to 43)

0.229

60(-37 to 157)

0.212

C vs E

136(80 to 192)

<0.001

186(104 to 268)

<0.001

121(46 to 195)

0.003

238(132 to 345)

<0.001

H vs E

15(-34 to 65)

0.525

54(-28 to 136)

0.184

77(7 to 147)

0.032

210(109 to 311)

<0.001

L:P

L:P

C vs H

6.0(-1.7 to 13.7)

0.122

9.2(0.6 to 17.8)

0.087

0.4(0.2 to 1.0)

0.193

0.6(-0.1 to 1.3)

0.092

C vs E

3.7(-4.6 to 12.0)

0.363

6.7(-2.5 to 15.9)

0.142

-0.2(-0.8 to 0.5)

0.577

-0.6(-1.3 to 0.2)

0.122

H vs E

-2.3(-9.8 to 5.3)

0.540

-6.0(-14.3 to 2.2)

0.144

-0.6(-1.2 to 0)

0.061

-0.9(-1.60.2)

0.014

  1. Mean and maximum differences from baseline and CIs are given. A positive mean or maximum difference indicates increased values in H or E groups compared to controls (C versus H and C versus E) and vice versa. Similarly, for H versus E a positive mean or maximum difference indicates an increase in the E group compared to the H group. P(mean) refers to intergroup differences over time using mixed models analysis. P(max) refers to post-hoc analyses at the time of maximal difference and are given as unadjusted P-values.