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Table 3 Six-Minute Walk Test, Timed Up and Go Test, Physical Function in ICU Test, Assessment of Quality of Life Instrument utility and Short Form 36 Health Survey, version 2 raw scores by study group a

From: Exercise rehabilitation for patients with critical illness: a randomized controlled trial with 12 months of follow-up

 

Measurement time point

  

Baseline

ICU discharge

Discharge to home

3 months post–ICU discharge

6 months post–ICU discharge

12 months post–ICU discharge

Outcome measure

 

n

Mean (SD)

n

Mean (SD)

n

Mean (SD)

n

Mean (SD)

n

Mean (SD)

n

Mean (SD)

6MWT (m)

Usual care

  

60

187.9 (126.1)

58

266.7 (136.8)

52

382.1 (139.4)

45

402.4 (166.6)

38

409.6 (158.5)

Intervention

  

63

146.4 (79.4)

59

244.2 (124.0)

48

384.5 (147.9)

44

394.2 (156.2)

41

433.8 (150.7)

TUG (s)

Usual care

  

60

36.1 (42.9)

57

12.9 (6.6)

53

11.6 (11.2)

48

12.9 (17.9)

40

14.2 (24.7)

Intervention

  

63

41.1 (43.2)

59

18.8 (24.5)

51

12.2 (10.0)

47

9.8 (5.1)

45

10.3 (6.2)

PFIT

Usual care

72

5.2 (3.0)

56

8.0 (1.5)

        

Intervention

72

5.1 (3.1)

61

7.7 (1.7)

        

AQoL (utility)

Usual care

56

0.6 (0.3)

    

66

0.5 (0.4)

63

0.6 (0.4)

57

0.5 (0.4)

Intervention

52

0.6 (0.3)

    

59

0.5 (0.4)

58

0.5 (0.4)

56

0.5 (0.4)

SF-36v2 PF

Usual care

56

42.8 (13.1)

    

52

42.3 (12.0)

48

42.4 (13.7)

38

44.0 (11.2)

Intervention

52

39.6 (15.3)

    

49

39.9 (14.4)

48

40.1 (14.7)

42

41.4 (12.5)

PCS

Usual care

56

41.7 (11.5)

    

51

42.1 (9.6)

47

44.4 (10.7)

38

46.2 (9.4)

Intervention

51

39.3 (12.9)

    

49

41.0 (11.4)

47

41.6 (13.2)

42

44.7 (10.9)

MCS

Usual care

56

44.3 (12.8)

    

51

46.3 (12.0)

47

46.2 (12.9)

38

44.7 (15.7)

 

Intervention

51

41.8 (13.3)

    

49

46.0 (13.9)

47

45.8 (12.9)

42

47.9 (12.3)

  1. a6MWT, Six-Minute Walk Test (meters), higher scores equal improved performance, normative value = 662 m; TUG, Timed Up and Go Test (seconds), lower scores equal improved performance, normative value = 9.19 s; PFIT, Physical Function in ICU Test, scored on the basis of Rasch analysis, interval score range 0 to 10, with higher scores indicating improved performance; AQoL, Assessment of Quality of Life Measure; consistent with utility theory, for those who died, the AQoL utility score was set at 0.00 and higher scores indicate higher utility; SF-36v2, Short Form 36 Health Survey, version 2, in which higher scores indicate improved performance; PF, SF-36v2 physical function domain; PCS, SF-36v2 physical component score, MCS, SF-36v2 mental component score. SF-36v2 results are presented as T-scores where the population mean is 50 and the SD is 10. With the SF-36v2, only survivors at each time point contribute data. Baseline AQoL and SF-36 were administered to participants as close as possible to enrollment in the trial as a “then test” whereby participants retrospectively estimated their premorbid health-related quality of life.