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Table 2 Baseline characteristics of patients with ALI/ARDS according to survival

From: Increased plasma levels of heparin-binding protein in patients with acute respiratory distress syndrome

Characteristic Nonsurvivors (n= 22) Survivors (n= 56) Pvalue
Demographics    
  Age (years) 68 (63 to 72) 60 (51 to 64) 0.041*
  Male 13 (59.1) 32 (57.1) 0.875
  Body mass index (kg/m2) 23 (20 to 24) 24 (20 to 26) 0.510
Main cause of ALI/ARDS    
  Pneumonia 9 (40.9) 29 (51.8) 0.387
  Nonpulmonary sepsis 7 (31.8) 13 (23.2) 0.434
  Hemorrhagic shock 3 (13.6) 5 (8.9) 0.840
  Aspiration 2 (9.1) 4 (7.1) 0856
  APACHE II score 21 (18 to 23) 15 (12 to 18) 0.036*
  SOFA score 8 (6 to 10) 5 (3 to 6) 0.041*
  LIS score 2.4 (1.7 to 3.1) 1.8 (1.2 to 2.6) 0.087
Ventilatory data    
  Mechanical ventilation 17 (77.3) 32 (57.1) 0.098
  Arterial pH 7.29 (7.21 to 7.36) 7.39 (7.32 to 7.45) 0.128
  Arterial lactate 2.0 (1.7 to 2.3) 1.6 (1.3 to 1.8) 0.219
  PO2/FiO2 142 (120 to 171) 189 (158 to 217) 0.045*
Echocardiography    
  Patients examined 17 (77.3) 48 (85.7) 0.368
  LVEF (%) 53 (49 to 55) 56 (50 to 62) 0.271
Hemodynamics    
  Patients examined 12 (54.5) 19 (33.9) 0.094
  PAOP (mmHg) 14 (10 to 17) 12 (7 to 15) 0.652
  Cardiac index (l/min/m2) 2.88 (2.41 to 3.05) 3.15 (2.66 to 3.31) 0.872
  SvO2 (%) 58 (52 to 63) 63 (57 to 68) 0.529
Laboratory findings    
  White blood cells (109/l) 14.8 (11.6 to 16.2) 11.2 (9.7 to 14.6) 0.198
  Platelets (109/l) 165 (138 to 198) 211 (159 to 258) 0.265
  APTT (seconds) 34 (28 to 37) 29 (25 to 33) 0.436
  Bilirubin (μmol/l) 13.1 (10.1 to 15.1) 9.6 (7.2 to 12.8) 0.196
  Glucose (mmol/l) 6.9 (5.6 to 7.4) 6.5 (5.4 to 7.0) 0.398
  Albumin (g/l) 27.1 (25.8 to 29.6) 31.5 (28.1 to 33.4) 0.233
  Creatinine (μmol/l) 81 (72 to 96) 72 (56 to 88) 0.378
  HBP (ng/ml) 23.90 (14.81 to 32.45) 16.01 (10.97 to 21.06) 0.012*
  1. Data presented as median (interquartile range) for continuous variables and number (%) for categorical variables. ALI, acute lung injury; APACHE, Acute Physiology and Chronic Health Evaluation; APTT, activated partial thromboplastin time; ARDS, acute respiratory distress syndrome; HBP, heparin-binding protein; LIS, Lung Injury Score; LVEF, left ventricular ejection fraction; PAOP, pulmonary artery occlusion pressure; PO2/FiO2, ratio of arterial oxygen partial pressure and inspiratory oxygen fraction; SOFA, Sequential Organ Failure Assessment; SvO2, oxygen saturation of venous blood. *P <0.05.