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Table 2 Baseline characteristics of patients with ALI/ARDS according to survival

From: Increased plasma levels of heparin-binding protein in patients with acute respiratory distress syndrome

Characteristic

Nonsurvivors (n= 22)

Survivors (n= 56)

Pvalue

Demographics

   

  Age (years)

68 (63 to 72)

60 (51 to 64)

0.041*

  Male

13 (59.1)

32 (57.1)

0.875

  Body mass index (kg/m2)

23 (20 to 24)

24 (20 to 26)

0.510

Main cause of ALI/ARDS

   

  Pneumonia

9 (40.9)

29 (51.8)

0.387

  Nonpulmonary sepsis

7 (31.8)

13 (23.2)

0.434

  Hemorrhagic shock

3 (13.6)

5 (8.9)

0.840

  Aspiration

2 (9.1)

4 (7.1)

0856

  APACHE II score

21 (18 to 23)

15 (12 to 18)

0.036*

  SOFA score

8 (6 to 10)

5 (3 to 6)

0.041*

  LIS score

2.4 (1.7 to 3.1)

1.8 (1.2 to 2.6)

0.087

Ventilatory data

   

  Mechanical ventilation

17 (77.3)

32 (57.1)

0.098

  Arterial pH

7.29 (7.21 to 7.36)

7.39 (7.32 to 7.45)

0.128

  Arterial lactate

2.0 (1.7 to 2.3)

1.6 (1.3 to 1.8)

0.219

  PO2/FiO2

142 (120 to 171)

189 (158 to 217)

0.045*

Echocardiography

   

  Patients examined

17 (77.3)

48 (85.7)

0.368

  LVEF (%)

53 (49 to 55)

56 (50 to 62)

0.271

Hemodynamics

   

  Patients examined

12 (54.5)

19 (33.9)

0.094

  PAOP (mmHg)

14 (10 to 17)

12 (7 to 15)

0.652

  Cardiac index (l/min/m2)

2.88 (2.41 to 3.05)

3.15 (2.66 to 3.31)

0.872

  SvO2 (%)

58 (52 to 63)

63 (57 to 68)

0.529

Laboratory findings

   

  White blood cells (109/l)

14.8 (11.6 to 16.2)

11.2 (9.7 to 14.6)

0.198

  Platelets (109/l)

165 (138 to 198)

211 (159 to 258)

0.265

  APTT (seconds)

34 (28 to 37)

29 (25 to 33)

0.436

  Bilirubin (μmol/l)

13.1 (10.1 to 15.1)

9.6 (7.2 to 12.8)

0.196

  Glucose (mmol/l)

6.9 (5.6 to 7.4)

6.5 (5.4 to 7.0)

0.398

  Albumin (g/l)

27.1 (25.8 to 29.6)

31.5 (28.1 to 33.4)

0.233

  Creatinine (μmol/l)

81 (72 to 96)

72 (56 to 88)

0.378

  HBP (ng/ml)

23.90 (14.81 to 32.45)

16.01 (10.97 to 21.06)

0.012*

  1. Data presented as median (interquartile range) for continuous variables and number (%) for categorical variables. ALI, acute lung injury; APACHE, Acute Physiology and Chronic Health Evaluation; APTT, activated partial thromboplastin time; ARDS, acute respiratory distress syndrome; HBP, heparin-binding protein; LIS, Lung Injury Score; LVEF, left ventricular ejection fraction; PAOP, pulmonary artery occlusion pressure; PO2/FiO2, ratio of arterial oxygen partial pressure and inspiratory oxygen fraction; SOFA, Sequential Organ Failure Assessment; SvO2, oxygen saturation of venous blood. *P <0.05.