Low-flow CO2removal integrated into a renal-replacement circuit can reduce acidosis and decrease vasopressor requirements

Table 3 Changes in systemic arterial pH, pCO₂, bicarbonate (HCO₃) from the beginning ( t = 0 hours), 4 hours ( t = 4 hours), and 24 hours ( t = 24 hours) after starting low-flow CO₂removal

No.	Art. pH			Art. pCO₂			Art. HCO₃
	t = 0	t = 4 hours	ΔpH	t = 0	t = 4 hours	ΔpCO₂	t = 0	t = 4 hours	ΔHCO₃
1	7.17	7.25	0.08	58	47	−11	20	20	0
2	7.24	7.28	0.04	56	51	−5	22	24	2
3	7.10	7.29	0.19	77	49	−28	23	23	0
4	7.18	7.34	0.16	69	52	−17	25	27	2
5	7.24	7.21^a	−0.03	88	90^a	2	37	34^a	−3
6	7.07	7.18	0.11	77	57	−20	20	19	−1
7	7.37	7.44	0.07	55	44	−11	31	30	−1
8	7.16	7.24	0.09	66	55	−11	23	23	0
9	7.18	7.31	0.13	79	55	−24	29	27	−2
10	7.18	7.37	0.19	65	36	−29	23	21	−2
Mean	7.18	7.30	0.12	69.00	49.56	−17.3	25.3	23.78	−0.22

Deltas indicate differences between t = 0 and t = 4 hours. Patient 5 was switched to ECMO after 2.5 hours of treatment and was therefore excluded from calculation of means and deltas at t = 4 hours. ^at = 2.5 hours.

ISSN: 1364-8535