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Table 3 Multivariate logistic regression analysis to assess factors associated with the realization of de-escalation

From: Factors influencing the implementation of antibiotic de-escalation and impact of this strategy in critically ill patients

Variable

Coefficient

Standard error

Chi-squared

P value

Odds ratio (95% CI)

Sex

−0.32

0.34

0.9

0.33

0.7 (0.4-1.4)

Coma

−0.21

0.47

0.2

0.66

0.8 (0.3-2.0)

Urinary tract infection

0.24

0.61

0.2

0.68

1.3 (0.4-4.2)

Previous antibiotherapy

0.63

0.41

2.3

0.13

1.9 (0.8-4.2)

Appropriate initial antibiotherapy

1.08

0.34

9.9

0.002

2.9 (1.5-5.7)

Narrow-spectrum antibiotic

−4.51

1.04

18.6

<0.001

0.1 (0.0-0.1)

MDR bacterial infection

−1.41

0.52

7.4

0.006

0.2 (0.1-0.7)

  1. CI, confidence interval; MDR, multidrug resistant.
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Critical Care

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