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Table 3 Multivariate logistic regression analysis to assess factors associated with the realization of de-escalation

From: Factors influencing the implementation of antibiotic de-escalation and impact of this strategy in critically ill patients

Variable Coefficient Standard error Chi-squared P value Odds ratio (95% CI)
Sex −0.32 0.34 0.9 0.33 0.7 (0.4-1.4)
Coma −0.21 0.47 0.2 0.66 0.8 (0.3-2.0)
Urinary tract infection 0.24 0.61 0.2 0.68 1.3 (0.4-4.2)
Previous antibiotherapy 0.63 0.41 2.3 0.13 1.9 (0.8-4.2)
Appropriate initial antibiotherapy 1.08 0.34 9.9 0.002 2.9 (1.5-5.7)
Narrow-spectrum antibiotic −4.51 1.04 18.6 <0.001 0.1 (0.0-0.1)
MDR bacterial infection −1.41 0.52 7.4 0.006 0.2 (0.1-0.7)
  1. CI, confidence interval; MDR, multidrug resistant.