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Table 6 Comparison between non-DIC, JAAM DIC and ISTH overt DIC on day of inclusion (day 1)

From: A multicenter, prospective validation study of the Japanese Association for Acute Medicine disseminated intravascular coagulation scoring system in patients with severe sepsis

 

All JAAM DIC

 

Non-DIC (n = 332)

JAAM DIC ( n = 179)

ISTH overt DIC ( n = 113)

P value

Age (years)

69 ± 18

70 ± 15

69 ± 16

0.484

Gender (male/female)

210/122

116/63

65/48

0.432

Septic shock (%)

35.5

51.4

63.7*

<0.001

Positive blood culture (%)

33.9

42.7

60.2**

<0.001

JAAM DIC score

1.9 ± 0.9

5.0 ± 0.9

6.7 ± 1.3***

<0.001

ISTH overt DIC score

1.3 ± 1.2

3.2 ± 0.9

5.7 ± 0.8***

<0.001

SIRS score

3.1 ± 0.9

3.2 ± 0.8

3.4 ± 0.8

0.012

APACHE II score

21.9 ± 7.8

24.6 ± 8.1

26.3 ± 9.0

<0.001

SOFA score

6.7 ± 3.3

9.9 ± 3.8

11.7 ± 3.5***

<0.001

MODS (%)

40.4

60.9

72.6*

<0.001

28-day outcome (death/%)

53/16.0

57/31.8

34/30.1

<0.001

Hospital outcome (death/%)

72/21.7

69/38.5

43/38.1

<0.001

  1. APACHE, Acute Physiology and Chronic Health Evaluation; DIC, disseminated intravascular coagulation; ISTH, International Society on Haemostasis and Thrombosis; JAAM, Japanese Association for Acute Medicine; MODS, multiple organ dysfunction syndrome; SIRS, Systemic inflammatory response syndrome; SOFA, Sequential Organ Failure Assessment. P values are between three groups. ISTH overt DIC refers to the patients meeting both the JAAM and the ISTH overt DIC criteria. *P <0.05, **P <0.01, ***P <0.001 versus JAAM DIC.