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Figure 1 | Critical Care

Figure 1

From: Septic serum induces glucocorticoid resistance and modifies the expression of glucocorticoid isoforms receptors: a prospective cohort study and in vitro experimental assay

Figure 1

Western blot analysis of glucocorticoid receptor α and β isoforms of peripheral blood mononuclear cells from septic patients. GRα and GRβ cell expression were evaluated by western blotting in peripheral blood mononuclear cells from septic patients on ICU admission (first day in the ICU) and on the day of hospital discharge, which was considered as the control situation (free of sepsis). The quantification of the western blot analysis of (A) GRα and (B) GRβ is shown. The values were normalized to β actin expression and are expressed as percentage values of the control (GR expression on the day of hospital discharge). Data are presented as median value, 25% to 75% (box) and minimum-maximum (vertical line). (C) Representative western blot analysis of GRαGRβ and β actin are shown. GR, glucocorticoid receptor; ICU, intensive care unit.

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Critical Care

ISSN: 1364-8535