Skip to main content

Table 2 Cardio-respiratory parameters in old and young mechanically ventilated rats

From: Susceptibility to ventilator induced lung injury is increased in senescent rats

 

VT 8

VT 8

VT 16

VT 16

VT 24

VT 24

 

beginning

end

beginning

end

Beginning

end

_pH

      

        old

7.44 (± 0.19)

7.42 (± 0.02)

7.39 (± 0.01)

7.36 (± 0.03)

7.41 (± 0.18)

7.24 (± 0.06)

        young

7.36 (± 0.02)

7.34 (± 0.01)

7.44 (± 0.19)

7.43 (± 0.13)

7.40 (± 0.01)

7.46 (± 0.02)

_paCO2 (mmHg)

      

        old

38.8 (± 2.1)

35.3 (± 2.6)

37.8 (± 1.5)

36.7 (± 1.1)

36.4 (± 0.9

34.8 (± 1.3)

        young

47.0 (± 1.9)

48.7 (± 1.5)

38.2 (± 1.6)

38.7 (± 1.0)

40.1 (± 1.2)

38.1 (± 1.0)

_CVP (mmHg)

      

        Old

5.1 (± 0.6)

5.0 (± 0.5)

5.9 (± 0.6)

5.3 (± 0.6)

5.1 (± 0.3)

6.0 (±0.7)

        young

4.9 (± 0.5)

4.3 (± 0.5)

5.3 (± 0.6)

5.1 (± 0.6)

6.9 (± 0.6)

5.9 (± 0.5)

_Heart rate (bpm)

      

        old

397 (± 11)

426 (± 15)

413 (± 10)

390 (± 23)

380 (± 16)

415 (±10)

        young

432 (± 15)

436 (± 8)

448 (± 7)

439 (± 9)

421 (± 7)

418 (± 9)

  1. _Parameters were assessed at the beginning and at the end of the mechanical ventilation period. Tidal volumes (VT) were 8, 16 or 24 ml/kg, respectively.