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Table 2 Cardio-respiratory parameters in old and young mechanically ventilated rats

From: Susceptibility to ventilator induced lung injury is increased in senescent rats

  VT 8 VT 8 VT 16 VT 16 VT 24 VT 24
  beginning end beginning end Beginning end
_pH       
        old 7.44 (± 0.19) 7.42 (± 0.02) 7.39 (± 0.01) 7.36 (± 0.03) 7.41 (± 0.18) 7.24 (± 0.06)
        young 7.36 (± 0.02) 7.34 (± 0.01) 7.44 (± 0.19) 7.43 (± 0.13) 7.40 (± 0.01) 7.46 (± 0.02)
_paCO2 (mmHg)       
        old 38.8 (± 2.1) 35.3 (± 2.6) 37.8 (± 1.5) 36.7 (± 1.1) 36.4 (± 0.9 34.8 (± 1.3)
        young 47.0 (± 1.9) 48.7 (± 1.5) 38.2 (± 1.6) 38.7 (± 1.0) 40.1 (± 1.2) 38.1 (± 1.0)
_CVP (mmHg)       
        Old 5.1 (± 0.6) 5.0 (± 0.5) 5.9 (± 0.6) 5.3 (± 0.6) 5.1 (± 0.3) 6.0 (±0.7)
        young 4.9 (± 0.5) 4.3 (± 0.5) 5.3 (± 0.6) 5.1 (± 0.6) 6.9 (± 0.6) 5.9 (± 0.5)
_Heart rate (bpm)       
        old 397 (± 11) 426 (± 15) 413 (± 10) 390 (± 23) 380 (± 16) 415 (±10)
        young 432 (± 15) 436 (± 8) 448 (± 7) 439 (± 9) 421 (± 7) 418 (± 9)
  1. _Parameters were assessed at the beginning and at the end of the mechanical ventilation period. Tidal volumes (VT) were 8, 16 or 24 ml/kg, respectively.