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Table

From: An investigation of the offset of pharmacodynamic effects of remifentanil following prolonged infusion in ICU patients with varying degrees of renal dysfunction: preliminary results

 

Renal status:

Renal status:

 

normal/mild PD

moderate/severe PD

Time of down

offset (min)

offset (min)

titration (h)

(mean, SD)

(mean, SD)

8

15.6 ± 7.4 (n = 10)

19 ± 15.7 (n = 27)

24

13.8 ± 7.7 (n = 10)

20.3 ± 11.7 (n = 20)

48

16.1 ± 7.2 (n = 8)

15.4 ± 7.4 (n = 12)

72

14.8 ± 5.7 (n = 6)

25.3 ± 12.6 (n = 11)

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Critical Care

ISSN: 1364-8535